CIENCIASMEDICASNEWS: How Patch Clamp Technology Can Benefit Ion Channel Research | Medical News

martes, 26 de febrero de 2019

How Patch Clamp Technology Can Benefit Ion Channel Research | Medical News | Medical Articles

	February 26, 2019
	Neurology / Neuroscience
	The latest neurology news from News Medical

How Patch Clamp Technology Can Benefit Ion Channel Research

Neuroscience relevant ion channels NaV1.8 and NaV1.9, are TTX resistant sodium channels expressed in the dorsal root ganglion neurons involved in pain sensation. These have proved a tricky target to approach because they do not express well in heterologous systems. In this interview, Nanion representatives discuss how their high throughput patch clamp technology instrumentation has shown recordings of these ion channels.

			Motor Neuron Disease: Can Dietary Supplements Help? Modifying the diet and nutritional intake of individuals with motor neuron disease (MND) is paramount in managing the disorder.

			RNAs are involved in protein aggregation and neurodegenerative diseases, research reveals New research reveals RNAs, which are crucial for cells to produce proteins, are also involved in protein aggregation, where proteins do not fold properly and 'clump' together into aggregates. If cells cannot clear these away, they become toxic and prevent cells working properly.

			Lifetime adversity, increased neural processing during trauma combine to intensify core PTSD symptoms Lifetime adversity and increased neural processing during a traumatic event combine to increase the frequency of intrusive traumatic memories and the distress they cause, according to a new study in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging.

			Target Proteins for the Imaging of Cholinergic Neurons Cholinergic neurons use the neurotransmitter acetylcholine to communicate with one another. During the progression of neurodegenerative diseases, which result in a loss of brain function, a reduction in the number of cholinergic neurons has been observed.