Cancer Information Highlights, April 11, 2018

Cancer Information Highlights, April 11, 2018

Cancer Information Highlights

From the National Cancer Institute

Updating you about cancer causes, prevention, screening, treatment, coping, and more

New from NCI Infographic—Genetic Changes and Cancer   Our new infographic shows some genetic changes that can lead to cancer. Can an Interactive App Improve Colorectal Cancer Screening Rates?   Colon and rectal cancer screening reduces deaths from the disease, yet about one-third of Americans aren’t up to date with screening. Learn what happened when people waiting for routine checkups used an app that allowed them to order their own screening test. Cancer Immunotherapy Drug Targets Two Proteins that Block Immune Response Could the hybrid molecule called a Y-trap be more effective than an immune checkpoint inhibitor alone, without increasing side effects? Higher Risk of Heart Failure Seen in Some Patients Treated for Cancer Heart failure is a problem in which weakened or damaged heart muscles are unable to effectively pump blood to the rest of the body. Read about research that shows which cancer patients may be at risk for developing this problem. Early Trial Results Show Promise for Patients with Rare Sarcomas Early results from an NCI-funded randomized clinical trial for patients with desmoid tumors or aggressive fibromatosis show that a targeted therapy improved the length of time they lived before their disease got worse. PDQ Summary Updates Childhood Non-Hodgkin Lymphoma (NHL) Treatment We’ve updated our PDQ summary on childhood NHL with treatment options for mucosa-associated lymphoid tissue (MALT) lymphoma, which is a type of NHL. Cognitive Impairment in Adults with Cancer We’ve added a new PDQ summary on cognitive impairment that occurs in adults treated for cancer that is not in the central nervous system. Treatment of Unusual Cancers of Childhood We’ve revised our PDQ summary on unusual childhood cancers with updated sections on radiation therapy, hormone therapy, and immunotherapy. Treatment options for neuroendocrine tumors and melanoma in children have also been updated. Drug Information Updates Brentuximab for Hodgkin Lymphoma The Food and Drug Administration (FDA)-approved indications for brentuximab vedotin (Adcetris) have been expanded to include treatment of adults with previously untreated stage III or stage IV Hodgkin lymphoma. Nilotinib Use in Leukemia We’ve updated our nilotinib drug information summary with a newly approved FDA indication. Nilotinib (Tasigna) is now approved for use in adults and children aged one year and older to treat certain types of chronic myelogenous leukemia that is Philadelphia chromosome positive.

Also of Interest NCI Contact Center The NCI Contact Center provides accurate, up-to-date, and reliable cancer information that is easy to understand. Trained information specialists provide personalized responses to a range of cancer questions, including help finding clinical trials and quitting smoking. Testicular Cancer Testicular cancer is the most common cancer in men 15 to 34 years old. Visit the Testicular Cancer page to learn about the types of testicular cancer, symptoms, and treatment. Chemicals in Meat Cooked at High Temperatures and Cancer Risk Chemicals can form on the surface of meats when they are cooked at high temperatures. Learn about these chemicals, how they are formed, and what is known about how they affect cancer risk.