Legionnaires' Disease
Legionnaires' Disease: Insights from Genomics - July 31, 2015
CDC information:Legionella (Legionnaires' Disease and Pontiac Fever)
Design and application of a core genome multilocus sequence typing scheme for investigation of Legionnaires' disease incidents.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Moran-Gilad J et al. Euro Surveill. 2015 (28)
Moran-Gilad J et al. Euro Surveill. 2015 (28)
Whole genome mapping as a novel high-resolution typing tool for Legionella pneumophila.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Bosch T et al. J. Clin. Microbiol. 2015 Jul 22.
Bosch T et al. J. Clin. Microbiol. 2015 Jul 22.
Comparative analyses of Legionella species identifies genetic features of strains causing Legionnaires' disease.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Gomez-Valero L et al. Genome Biol. 2014 (11) 505
Gomez-Valero L et al. Genome Biol. 2014 (11) 505
Recombination drives genome evolution in outbreak-related Legionella pneumophila isolates.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Sánchez-Busó L et al. Nat. Genet. 2014 Nov (11) 1205-11
Sánchez-Busó L et al. Nat. Genet. 2014 Nov (11) 1205-11
Genomic characterization of a large outbreak of Legionella pneumophila serogroup 1 strains in Quebec City, 2012.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Lévesque S et al. PLoS ONE 2014 (8) e103852
Lévesque S et al. PLoS ONE 2014 (8) e103852
Real-time investigation of a Legionella pneumophila outbreak using whole genome sequencing.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Graham RMA et al. Epidemiol. Infect. 2014 Nov (11) 2347-51
Graham RMA et al. Epidemiol. Infect. 2014 Nov (11) 2347-51
Comparative analyses of Legionella species identifies genetic features of strains causing Legionnaires' disease.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Gomez-Valero L et al. Genome Biol. 2014 (11) 505
Gomez-Valero L et al. Genome Biol. 2014 (11) 505
CDC Advanced Molecular Detection Initiative: Rapid molecular detection of Legionella for outbreak response
Recent Genomic Insights
Recent Genomic Insights
Gene flow in environmental Legionella pneumophila leads to genetic and pathogenic heterogeneity within a Legionnaires' disease outbreak.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
McAdam PR et al. Genome Biol. 2014 (11) 504
A new oligonucleotide microarray for detection of pathogenic and non-pathogenic Legionella spp.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Cao B, et al. PLoS One. 2014 Dec 3;9(12):e113863
McAdam PR et al. Genome Biol. 2014 (11) 504
A new oligonucleotide microarray for detection of pathogenic and non-pathogenic Legionella spp.
Cao B, et al. PLoS One. 2014 Dec 3;9(12):e113863
Comparative genomics reveal that host-innate immune responses influence the clinical prevalence of Legionella pneumophila serogroups.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Khan MA, et al. PLoS One. 2013 Jun 27;8(6):e67298. Print 2013
Khan MA, et al. PLoS One. 2013 Jun 27;8(6):e67298. Print 2013
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