Genomics|Update|Non Communicable Diseases ►Cancer

Genomics|Update|Non Communicable Diseases

Volume 35  Number 9  August 27 - September 3, 2015

Cancer

Association between mutation clearance after induction therapy and outcomes in acute myeloid leukemia. 
Klco JM et al. JAMA 2015 Aug 25. 314(8) 811-822

Development and validation of a next-generation sequencing assay for BRCA1 and BRCA2 variants for the clinical laboratory. 
Strom CM et al. PLoS ONE 2015 10(8) e0136419

Does molecular monitoring matter in early-stage breast cancer? 
Sundaresan TK, et al. Science Translational Medicine 26 Aug 2015

Efficacy of a web-based intelligent tutoring system for communicating genetic risk of breast cancer: a fuzzy-trace theory approach. 
Wolfe CR et al. Med Decis Making 2015 Jan 35(1) 46-59 

Is it time to offer BRCA1 and BRCA2 testing to all Jewish women? 
Metcalfe KA et al. Curr Oncol 2015 Aug 22(4) e233-6

Mutation tracking in circulating tumor DNA predicts relapse in early breast cancer 
Garcia-Murillas I, et al. Science Translational Medicine 26 Aug 2015

New ‘mutation-tracking’ blood test could predict breast cancer relapse months in advance,the Institute of Cancer Research, Aug 26

NCI-MATCH launch highlights new trial design in precision-medicine era.
McNeil C. J Natl Cancer Inst. 2015 Jul 3;107(7). pii: djv193.

Next-generation sequencing and detection of minimal residual disease in acute myeloid leukemia: Ready for clinical practice? 
Pastore F et al. JAMA 2015 Aug 25. 314(8) 778-780

Rescreening for genetic mutations using multi-gene panel testing in patients who previously underwent non-informative genetic screening. 
Frey MK et al. Gynecol. Oncol. 2015 Aug 18.

Screening strategies for colorectal cancer among patients with non-alcoholic fatty liver disease and family history. 
Wong MC et al. Int. J. Cancer 2015 Aug 20.

The role of germline mutations in the BRCA1/2 and mismatch repair genes in men ascertained for early-onset and/or familial prostate cancer.
Maia S, et al. Fam Cancer. 2015 Aug 20.

Women with double primary cancers of the colorectum and endometrium: do they have Lynch syndrome? 
Song T et al. Eur. J. Obstet. Gynecol. Reprod. Biol. 2015 Aug 19.

Initial medical policy and model coverage guidelines for clinical NGS in oncology, [PDF 965.34 KB] 
Green Park Collaborative, Aug 17