Chikungunya: Recent Genomics and Public Health Insights - July 28, 2015

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Chikungunya

Chikungunya: Recent Genomics and Public Health Insights - July 28, 2015

CDC Info

• Complete genome sequence of chikungunya virus isolated from an Aedes aegypti mosquito during an outbreak in Yemen, 2011.Fahmy NT et al.Genome Announc 2015 (4)
• Chikungunya virus
• Notes from the field: Chikungunya virus spreads in the Americas — Caribbean and South America, 2013–2014.
  MMWR 2014. 63(22);500-501.

Complete genome sequence of chikungunya virus isolated from an Aedes aegypti mosquito during an outbreak in Yemen, 2011.
Fahmy NT et al.Genome Announc 2015 (4)

A systematic meta-analysis of immune signatures in patients with acute chikungunya virus infection.
Teng Terk-Shin et al. J. Infect. Dis. 2015 Jun 15. (12) 1925-35

Dengue and Chikungunya in our backyard: Preventing Aedes mosquito-borne disease, CDC Public Health Grand Rounds, May 2015

The burden of Dengue and Chikungunya worldwide: Implications for the Southern United States and California.
Fredericks AC et al. Ann Glob Health 2014 Nov-Dec (6) 466-475

Therapeutics and vaccines against chikungunya virus.
Ahola T et al. Vector Borne Zoonotic Dis. 2015 Apr (4) 250-7

Updates on chikungunya epidemiology, clinical disease, and diagnostics.
Sam I-Ching et al. Vector Borne Zoonotic Dis. 2015 Apr (4) 223-30

Chikungunya virus and the global spread of a mosquito-borne disease.
Weaver SC et al. N. Engl. J. Med. 2015 Mar 26. (13) 1231-9

High throughput proteomic analysis and a comparative review identify the nuclear chaperone, Nucleophosmin among the common set of proteins modulated in Chikungunya virus infection.
Abraham R et al. J Proteomics 2015 Apr 29. 126-41

New approaches to chikungunya virus vaccine development.
Garcia A et al. Recent Pat Inflamm Allergy Drug Discov 2015 (1) 31-7

Chikungunya virus and its mosquito vectors.
Higgs S et al. Vector Borne Zoonotic Dis. 2015 Apr (4) 231-40

Chikungunya: Establishing a new home in the western hemisphere.
Davidson H. Hamer et al. Annals of Internal Medicine, December 2014

While Americans watched for Ebola in 2014, another painful virus slipped into the U.S. and it's just getting started, NPR News, Jan 1, 2015

Next generation sequencing reveals regulation of distinct Aedes microRNAs during chikungunya virus development. 
Shrinet J, et al. PLoS Negl Trop Dis. 2014 Jan 9;8(1):e2616

Comprehensive proteomic analysis of white blood cells from chikungunya fever patients of different severities. 
Wikan N, et al. J Transl Med. 2014 Apr 11;12:96.

Multiple immune factors are involved in controlling acute and chronic chikungunya virus infection 
Poo YS, et al. PLoS Negl Trop Dis. 2014 Dec 4;8(12):e3354

Chikungunya: Genomics and Public Health - August 21, 2014

CDC information on chikungunya virus & its transmission

CDC notes from the field: Chikungunya virus spreads in the Americas — Caribbean and South America, 2013–2014.
MMWR 2014. 63(22);500-501.

US assesses virus of the Caribbean. Researchers warn that a change of mosquito host could accelerate spread of chikungunya across the Americas, Aleszu Bajak, Nature News, Aug 12

Comparative analysis of the genome sequences and replication profiles of chikungunya virus isolates within the East, Central and South African (ECSA) lineage. 
Karen Caiyun Chen et al. Virology Journal (2013)

Complete genome sequence of a chikungunya virus isolated in Guangdong, China. 
Xiao-Feng Li et al. Journal of Virology (2012)

Gene x Gene x Environment: Chikungunya virus is transmitted through a three-way interaction that hinges on viral strain, mosquito genotype, and ambient temperature, researchers have found, by Sandhya Sekar, The Scientist, Aug 12