Genomics|Update|Infectious Diseases ►Antimicrobials, Vaccines, Interventions [5]

Genomics|Update|Infectious Diseases

Antimicrobials, Vaccines, Interventions

Molecular mechanisms of antibiotic resistance
Blair JMA, et al. Nat Rev Microbiol 2015; 14:32-51.

Genomic analysis of isolates from the UK 2012 pertussis outbreak reveals that vaccine antigen genes are unusually fast evolving
Sealey KL, et al. J Infect Dis, 2014 Dec 8.

Characterization of a multidrug-resistant, novel Bacteroides genomospecies
Salipante SJ, et al. Emerg Infect Dis, Jan 2015.

Glucose- but not rice-based oral rehydration therapy enhances the production of virulence determinants in the human pathogen Vibrio cholerae
Kuhn J, et al. PLoS Negl Trop Dis 2014; 8(12): e3347.

Use of highly pathogenic avian influenza A(H5N1) gain-of-function studies for molecular-based surveillance and pandemic preparedness
Davis CT, et al. mBio 2014; 5(6): e02431-14.

Influenza gain-of-function experiments: their role in vaccine virus recommendation and pandemic preparedness
Schultz-Cherry S, et al. mBio 2014; 5(6): e02430-14.

Comment:

mBio addresses the pause in gain-of-function (GOF) experiments involving pathogens with pandemic potential (PPP)
Casadevall A, Schenk T. mBio 2014; 5(6): e02434-14.

Special issue on ‘Genetic diversity and evolution of rotavirus strains: Possible impact of global immunization programs’
Banyai K, Gentsch J. Infect Genet Evol 2014; 28: 375–376.

Population transcriptomics of human malaria parasites reveals the mechanism of artemisinin resistance
Mok S, et al. Science, Dec 11, 2014.

Comment:

The genetics of resistant malaria
Vogel G.  Science, Dec 12, 2014.