domingo, 25 de mayo de 2014

Nutrigenomics: Definitions and Advances of This New Science

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Nutrigenomics: Definitions and Advances of This New Science



J Nutr Metab. 2014; 2014: 202759.
Published online Mar 25, 2014. doi:  10.1155/2014/202759
PMCID: PMC3984860

Nutrigenomics: Definitions and Advances of This New Science

1. Introduction

Food intake and the environment are the two main factors that affect the health or illness of an individual []. Studies in nutritional area have increased the understanding of how to maintain healthy a group of individuals that live in different dietary conditions []. However, after the conclusion of the Human Genome Project (HGP), new insights about the influence of nutrients into people's diet were postulated, which included (i) will gene expression in response to metabolic process, at cellular level, influence the health of an individual? (ii) Are gene expression and metabolic response the result of the interaction between genotype and environment/nutrient? (iii) Understanding how this interaction process occurs between gene and nutrient could lead to the prescription of specific diets for each individual. Hence, in order to answer those questions, Nutrigenomics was introduced [,]. The studies on Nutrigenomics are focused on the effects of the nutrients over the genome, proteome, and metabolome, as illustrated on Figure 1 [].

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