Update: Detection of a Verona Integron-Encoded Metallo-Beta-Lactamase in Klebsiella pneumoniae --- United States, 2010

Update: Detection of a Verona Integron-Encoded Metallo-Beta-Lactamase in Klebsiella pneumoniae — United States, 2010

In July, CDC learned of a patient with a carbapenem-resistant Klebsiella pneumoniae strain that produced a Verona integron-encoded metallo-beta-lactamase carbapenemase not reported previously among Enterobacteriaceae in the United States. The patient became ill during a cruise and was first hospitalized in Greece and then in the United States. Testing showed the isolate to be nonsusceptible to all antimicrobials usually used to treat Klebsiella. Despite this resistance, the patient recovered sufficiently to be discharged after 26 days in the U.S. hospital. This report follows a June report of three cases of New Delhi metallo-beta-lactamase–producing Enterobacteriaceae. However, the most common mechanism of carbapenem resistance among Enterobacteriaceae in the United States remains production of the Klebsiella pneumoniae carbapenemase.

open here to see the full-text:
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm59e0921a1.htm?s_cid=mm59e0921a1_w