lunes, 3 de febrero de 2020

BMC Cancer | Articles

BMC Cancer | Articles



  1. Lymphovascular invasion (LVI) is a vital risk factor for prognosis across cancers. We aimed to develop a scoring system for stratifying LVI risk in patients with breast cancer.
    Authors:Ma-yi-di-li Ni-jia-ti, Di-li-a-re-mu Ai-hai-ti, Ai-si-ka-er-jiang Huo-jia, Pa-li-dan-mu Wu-mai-er, A-bu-du-ke-you-mu-jiang A-bu-li-zi, Yu Shi, Nu-er-a-mi-na Rou-zi, Wen-jing Su, Guo-zhao Dai and Mai-he-mi-ti-jiang Da-mo-la
    Citation:BMC Cancer 2020 20:94
    Content type:Research article
    Published on: 
  2. Pembrolizumab is effective as first-line therapy against advanced non-small cell lung cancer (NSCLC) in patients with programmed death ligand-1 (PD-L1) expression levels ≥50% [1]. However, it is not effective ...
    Authors:Mitsunori Morita, Motohiro Tamiya, Daichi Fujimoto, Akihiro Tamiya, Hidekazu Suzuki, Katsuya Hirano, Yasushi Fukuda, Toshihide Yokoyama, Ryota Kominami, Masaki Kanazu, Junji Uchida, Satoshi Hara, Shuji Yamashita and Hiromi Tomioka
    Citation:BMC Cancer 2020 20:93
    Content type:Research article
    Published on: 
  3. Following publication of the original article [1], an error was reported in the author group. The correct author group should read as follows:
    Authors:Anita Feller, Katarina L. Matthes, Andrea Bordoni, Christine Bouchardy, Jean-Luc Bulliard, Christian Herrmann, Isabelle Konzelmann, Manuela Maspoli, Mohsen Mousavi, Sabine Rohrmann, Katharina Staehelin and Volker Arndt
    Citation:BMC Cancer 2020 20:87
    Content type:Correction
    Published on: 
    The original article was published in BMC Cancer 2020 20:51
  4. Interrogation of site-specific CpG methylation in circulating tumor DNAs (ctDNAs) has been employed in a number of studies for early detection of breast cancer (BrCa). In many of these studies, the markers wer...
    Authors:Manny D. Bacolod, Jianmin Huang, Sarah F. Giardina, Philip B. Feinberg, Aashiq H. Mirza, Alexander Swistel, Steven A. Soper and Francis Barany
    Citation:BMC Cancer 2020 20:85
    Content type:Research article
    Published on: 
  5. Cancer subtyping has mainly relied on pathological and molecular means. Massively parallel sequencing-enabled subtyping requires genomic markers to be developed based on global features rather than individual ...
    Authors:Zhenggang Wu, Xi Long, Shui Ying Tsang, Taobo Hu, Jian-Feng Yang, Wai Kin Mat, Hongyang Wang and Hong Xue
    Citation:BMC Cancer 2020 20:84
    Content type:Research article
    Published on: 
  6. Gene expression profiling has consistently identified three molecular subtypes of lung adenocarcinoma that have prognostic implications. To facilitate stratification of patients with this disease into similar ...
    Authors:Roberto Ruiz-Cordero, Junsheng Ma, Abha Khanna, Genevieve Lyons, Waree Rinsurongkawong, Roland Bassett, Ming Guo, Mark J. Routbort, Jianjun Zhang, Ferdinandos Skoulidis, John Heymach, Emily B. Roarty, Zhenya Tang, L. Jeffrey Medeiros, Keyur P. Patel, Rajyalakshmi Luthra…
    Citation:BMC Cancer 2020 20:83
    Content type:Research article
    Published on: 
  7. Although the pancreatic ductal adenocarcinoma (PDAC) presents high mortality and metastatic potential, there is a lack of effective therapies and a low survival rate for this disease. This PDAC scenario urges ...
    Authors:Palloma Porto Almeida, Cristina Padre Cardoso and Leandro Martins de Freitas
    Citation:BMC Cancer 2020 20:82
    Content type:Software
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  8. Increased usage of genomic risk assessment assays suggests increased reliance on data provided by these assays to guide therapy decisions. The current study aimed to assess the change in treatment decision and...
    Authors:Hatem Soliman, Varsha Shah, Gordan Srkalovic, Reshma Mahtani, Ellis Levine, Blanche Mavromatis, Jayanthi Srinivasiah, Mohamad Kassar, Robert Gabordi, Rubina Qamar, Sarah Untch, Heather M. Kling, Tina Treece and William Audeh
    Citation:BMC Cancer 2020 20:81
    Content type:Research article
    Published on: 
  9. Multi-arm designs provide an effective means of evaluating several treatments within the same clinical trial. Given the large number of treatments now available for testing in many disease areas, it has been a...
    Authors:Michael J. Grayling and James MS. Wason
    Citation:BMC Cancer 2020 20:80
    Content type:Software
    Published on: 
  10. Gliomas consist of a heterogeneous group of tumors. This study aimed to report the incidences of O6-methylguanine-DNA-methyltransferase (MGMT) promoter methylation, 1p19q co-deletion, isocitrate dehydrogenase (ID...
    Authors:Samantha Ya Lyn Ang, Lester Lee, Angela An Qi See, Ting Yao Ang, Beng Ti Ang and Nicolas Kon Kam King
    Citation:BMC Cancer 2020 20:79
    Content type:Research article
    Published on: 
  11. Although immediate breast reconstruction has been reported to be oncologically safe, no affirmative study comparing the two reconstruction methods exists. We investigated breast cancer recurrence rates in two ...
    Authors:Jeong Hyun Ha, Ki Yong Hong, Han-Byoel Lee, Hyeong-Gon Moon, Wonshik Han, Dong-Young Noh, Joonho Lim, Sehoon Yoon, Hak Chang and Ung Sik Jin
    Citation:BMC Cancer 2020 20:78
    Content type:Research article
    Published on: 
  12. The prognosis of non-small-cell lung cancer (NSCLC) with brain metastases is very poor. Currently, therapeutic methods for this patient population include whole-brain radiation therapy (WBRT), surgery, radiosu...
    Authors:Kejun Liu, Guanming Jiang, Ailing Zhang, Zhuanghua Li and Jun Jia
    Citation:BMC Cancer 2020 20:76
    Content type:Research article
    Published on: 
  13. Carbon ion Radiotherapy for prostate cancer is widely used, however reports are limited from single institute or short follow up. We performed a prospective observational study (GUNMA0702) to evaluate the feas...
    Authors:Hidemasa Kawamura, Nobuteru Kubo, Hiro Sato, Tatsuji Mizukami, Hiroyuki Katoh, Hitoshi Ishikawa, Tatsuya Ohno, Hiroshi Matsui, Kazuto Ito, Kazuhiro Suzuki and Takashi Nakano
    Citation:BMC Cancer 2020 20:75
    Content type:Research article
    Published on: 
  14. Approximately 40% of colorectal cancer patients will develop colorectal liver metastases (CRLM). The most effective approach to increase long-term survival is CRLM complete resection. Unfortunately, only 10–15...
    Authors:Alice Boilève, Aline Maillard, Mathilde Wagner, Clarisse Dromain, Christophe Laurent, Eric Dupont Bierre, Samuel Le Sourd, Franck Audemar, Ayhan Ulusakarya, Veronique Guerin-Meyer, Denis Smisth, Veronica Pezzella, Thierry De Baere, Diane Goere, Maximiliano Gelli, Julien Taieb…
    Citation:BMC Cancer 2020 20:74
    Content type:Study protocol
    Published on: 
  15. This study aimed to compare clinical outcomes following placement of fully covered self-expanding metallic stents (FCSEMS) vs partially covered self-expanding metallic stents (PCSEMS) for palliative treatment ...
    Authors:Chunmei Wang, Hua Wei and Yuxia Li
    Citation:BMC Cancer 2020 20:73
    Content type:Research article
    Published on: 
  16. Breast cancer (BC) is known to be the most common malignancy in females whereas colorectal cancer (CRC) incidence also higher in both genders in Sri Lanka. TP53 is an important tumour suppressor gene and its soma...
    Authors:Vahinipriya Manoharan, Eric Hamilton Karunanayake, Kamani Hemamala Tennekoon, Sumadee De Silva, Ahamed Ilyas Ahamed Imthikab, Kanishka De Silva, Preethika Angunawela, Sameera Vishwakula and John Lunec
    Citation:BMC Cancer 2020 20:72
    Content type:Research article
    Published on: 
  17. Kaposi’s sarcoma (KS) is one of the most common HIV-associated malignancies in sub-Saharan Africa. Worldwide, the availability of antiretroviral therapy (ART) has improved KS survival. In resource-rich setting...
    Authors:Esther E. Freeman, Naftali Busakhala, Susan Regan, Fredrick Chite Asirwa, Megan Wenger, Divya Seth, Khatiya Chelidze Moon, Aggrey Semeere, Toby Maurer, Kara Wools-Kaloustian, Ingrid Bassett and Jeffrey Martin
    Citation:BMC Cancer 2020 20:71
    Content type:Research article
    Published on: 
  18. Second primary cancer of the esophagus is frequent in head and neck patients, especially in high-risk populations, and has a great impact on the prognosis. Although Positron emission tomography (PET)/computed ...
    Authors:Hsuan-An Su, Shun-Wen Hsiao, Yu-Chun Hsu, Lien-Yen Wang and Hsu-Heng Yen
    Citation:BMC Cancer 2020 20:69
    Content type:Research article
    Published on: 
  19. The antibody targeting platelet-derived growth factor receptor alpha (PDGFRA), olaratumab, was approved in 2016 for metastatic soft tissue sarcoma (STS) in combination with doxorubicin based on promising resul...
    Authors:Jana Käthe Striefler, Franziska Brandes, Alexander Baur, Berit Maria Pfitzner, David Kaul, Daniel Rau, Anne Dörr, Maren Schmiester, Georgios Koulaxouzidis, Lars Bullinger, Sven Märdian and Anne Flörcken
    Citation:BMC Cancer 2020 20:68
    Content type:Research article
    Published on: 
  20. We previously reported that tamoxifen (TAM)-induced ovarian hyperstimulation (OHS) is associated with high serum concentrations of estradiol in premenopausal women with breast cancer. To investigate risk facto...
    Authors:Rena Yamazaki, Masafumi Inokuchi, Satoko Ishikawa, Takuya Ayabe, Hiromitsu Jinno, Takashi Iizuka, Masanori Ono, Subaru Myojo, Soko Uchida, Toshiya Matsuzaki, Akira Tangoku, Masato Kita, Tomoharu Sugie and Hiroshi Fujiwara
    Citation:BMC Cancer 2020 20:67
    Content type:Research article
    Published on: 
  21. We sought to construct the optimal neurocognitive function (NCF) change criteria sensitive to health-related quality of life (HR-QOL) in patients who have undergone whole-brain radiation therapy (WBRT) for bra...
    Authors:Toshimichi Nakano, Hidefumi Aoyama, Hirotake Saito, Satoshi Tanabe, Kensuke Tanaka, Katsuya Maruyama, Tomoya Oshikane, Atsushi Ohta, Eisuke Abe and Motoki Kaidu
    Citation:BMC Cancer 2020 20:66
    Content type:Research article
    Published on: 
  22. It is still difficult to detect and diagnose early adenocarcinoma of the esophagogastric junction (EGJ) using conventional endoscopy or image-enhanced endoscopy. A glutamylprolyl hydroxymethyl rhodamine green ...
    Authors:Keiko Yamamoto, Shunsuke Ohnishi, Takeshi Mizushima, Junichi Kodaira, Masayoshi Ono, Yutaka Hatanaka, Kanako C. Hatanaka, Yugo Kuriki, Mako Kamiya, Nobuyuki Ehira, Keisuke Shinada, Hiroaki Takahashi, Yuichi Shimizu, Yasuteru Urano and Naoya Sakamoto
    Citation:BMC Cancer 2020 20:64
    Content type:Research article
    Published on: 
  23. Cervical cancer is the most common cancer and the leading cause of cancer death among women in Tanzania. Knowledge of and willingness to receive a cervical cancer screening are important determinants of preven...
    Authors:Qiao Weng, Jie Jiang, Fatma Mrisho Haji, Lamlet Hassan Nondo and Huaijun Zhou
    Citation:BMC Cancer 2020 20:63
    Content type:Research article
    Published on: 
  24. Overexpression of FAT1 gene and its oncogenic effects have been reported in several cancers. Previously, we have documented upregulation of FAT1 gene in glioblastoma (GBM) tumors which was found to increase th...
    Authors:Chitrangda Srivastava, Khushboo Irshad, Yakhlesh Gupta, Chitra Sarkar, Ashish Suri, Parthaprasad Chattopadhyay, Subrata Sinha and Kunzang Chosdol
    Citation:BMC Cancer 2020 20:62
    Content type:Research article
    Published on: 
  25. To explore the influencing factors of perioperative renal function change and their relationship with prognosis on renal cell carcinoma (RCC) patients with tumor thrombus after nephrectomy and thrombectomy.
    Authors:Zhuo Liu, Shiying Tang, Xiaojun Tian, Hongxian Zhang, Guoliang Wang, Shudong Zhang and Lulin Ma
    Citation:BMC Cancer 2020 20:61
    Content type:Research article
    Published on: 
  26. This study aimed to evaluate the safety and feasibility of self-expanding metallic stent (SEMS) followed by neoadjuvant chemotherapy prior to elective surgery for obstructing left-sided colon cancer.
    Authors:Jia Gang Han, Zhen Jun Wang, Wei Gen Zeng, Yan Bin Wang, Guang Hui Wei, Zhi Wei Zhai, Bao Cheng Zhao and Bing Qiang Yi
    Citation:BMC Cancer 2020 20:57
    Content type:Research article
    Published on: 
  27. The presence of comorbidity affects the care of cancer patients, many of whom are living with multiple comorbidities. The prevalence of cancer comorbidity, beyond summary metrics, is not well known. This study...
    Authors:Helen Fowler, Aurelien Belot, Libby Ellis, Camille Maringe, Miguel Angel Luque-Fernandez, Edmund Njeru Njagi, Neal Navani, Diana Sarfati and Bernard Rachet
    Citation:BMC Cancer 2020 20:2
    Content type:Research article
    Published on: 
  28. Hepatocellular carcinoma (HCC) with hilar bile duct tumor thrombus (HBDTT) often mimic hilar cholangiocarcinoma (hilar CC). The purpose of this study is to analyze the Computed Tomography (CT) characteristics ...
    Authors:Xiaoqi Zhou, Jifei Wang, Mimi Tang, Mengqi Huang, Ling Xu, Zhenpeng Peng, Zi-Ping Li and Shi-Ting Feng
    Citation:BMC Cancer 2020 20:54
    Content type:Research article
    Published on: 
  29. Study aimed to characterise treatment and outcomes for patients with hormone receptor positive (HR+), human epidermal growth factor 2 negative (HER2-) metastatic breast cancer (MBC) within a large regional can...
    Authors:Chris Twelves, Sue Cheeseman, Will Sopwith, Matthew Thompson, Majid Riaz, Necibe Ahat-Donker, Melissa Myland, Adam Lee, Raymond Przybysz, Stuart Turner, Geoff Hall and Tim Perren
    Citation:BMC Cancer 2020 20:53
    Content type:Research article
    Published on: 
  30. The incidence of anal cancer is rising in the last decades and more women are affected than men. The prognosis after chemoradiation is very good with complete remission rates of 80–90%. Thus, reducing therapy-...
    Authors:Nathalie Arians, Matthias Häfner, Johannes Krisam, Kristin Lang, Antje Wark, Stefan A. Koerber, Adriane Hommertgen and Jürgen Debus
    Citation:BMC Cancer 2020 20:52
    Content type:Study protocol
    Published on: 
  31. More people than ever before are currently living with a diagnosis of cancer and the number of people concerned is likely to continue to rise. Cancer survivors are at risk of developing a second primary cancer...
    Authors:Anita Feller, Katarina L. Matthes, Andrea Bordoni, Christine Bouchardy, Jean-Luc Bulliard, Christian Herrmann, Isabelle Konzelmann, Manuela Maspoli, Mohsen Mousavi, Sabine Rohrmann, Katharina Staehelin and Volker Arndt
    Citation:BMC Cancer 2020 20:51
    Content type:Research article
    Published on: 
    The Correction to this article has been published in BMC Cancer 2020 20:87
  32. Screening for and active management of comorbidity soon after cancer diagnosis shows promise in altering cancer treatment and outcomes for comorbid patients. Prior to a large multi-centre study, piloting of th...
    Authors:Virginia Signal, Christopher Jackson, Louise Signal, Claire Hardie, Kirsten Holst, Marie McLaughlin, Courtney Steele and Diana Sarfati
    Citation:BMC Cancer 2020 20:50
    Content type:Research article
    Published on: 
  33. Preoperative chemoradiotherapy is the recommended standard of care for patients with local advanced rectal cancer. However, it remains unclear, whether a prolonged time interval to surgery results in an increa...
    Authors:Sven Lichthardt, Johanna Wagner, Stefan Löb, Niels Matthes, Caroline Kastner, Friedrich Anger, Christoph-Thomas Germer and Armin Wiegering
    Citation:BMC Cancer 2020 20:49
    Content type:Research article
    Published on: 
  34. Leukemia is the most common cancer in childhood. The estimated incidence rate of childhood leukemia in Colombia is one of the highest in America and little is known about its spatial distribution.
    Authors:Laura Andrea Rodriguez-Villamizar, Marcela Pilar Rojas Díaz, Lizbeth Alexandra Acuña Merchán, Feisar Enrique Moreno-Corzo and Paula Ramírez-Barbosa
    Citation:BMC Cancer 2020 20:48
    Content type:Research article
    Published on: 
  35. Glioblastoma (GBM) is a highly malignant brain neoplasm with poor survival. Despite its aggressive nature, metastatic spread of GBM is identified only rarely. While the molecular alterations associated with GB...
    Authors:Melissa Umphlett, Stephanie Shea, Jessica Tome-Garcia, Yizhou Zhang, Adilia Hormigo, Mary Fowkes, Nadejda M. Tsankova and Raymund L. Yong
    Citation:BMC Cancer 2020 20:47
    Content type:Case report
    Published on: 
  36. Breast (BCa) and prostate (PCa) cancers are hormone receptor (HR)-driven cancers. Thus, BCa and PCa patients are given therapies that reduce hormone levels or directly block HR activity; but most patients even...
    Authors:Afshan F. Nawas, Mohammed Kanchwala, Shayna E. Thomas-Jardin, Haley Dahl, Kelly Daescu, Monica Bautista, Vanessa Anunobi, Ally Wong, Rachel Meade, Ragini Mistry, Nisha Ghatwai, Felix Bayerl, Chao Xing and Nikki A. Delk
    Citation:BMC Cancer 2020 20:46
    Content type:Research article
    Published on: 
  37. Pancreatic cancer is a highly malignant tumor of the digestive system. This secretome of pancreatic cancer is key to its progression and metastasis. But different methods of protein extraction affect the final...
    Authors:Peng Liu, Lingming Kong, Keke Liang, Yunhao Wu, Haoyi Jin, Bing Song and Xiaodong Tan
    Citation:BMC Cancer 2020 20:45
    Content type:Research article
    Published on: 
  38. The aim of this retrospective study was to compare the feasibility and efficiency of ultrasound-guided percutaneous microwave ablation (US-PMWA) assisted by three-dimensional visualization ablation planning sy...
    Authors:Chao An, Xin Li, Min Zhang, Jian Yang, Zhigang Cheng, Xiaoling Yu, Zhiyu Han, Fangyi Liu, Linan Dong, Jie Yu and Ping Liang
    Citation:BMC Cancer 2020 20:44
    Content type:Research article
    Published on: 
  39. Following publication of the original article [1], the authors reported the errors in Fig. 1C and D, Fig. 2, Fig. 4B and C and Fig. 6D and E.
    Authors:Yanan Jiang, Jing Zhang, Jimin Zhao, Zhenzhen Li, Hanyong Chen, Yan Qiao, Xinhuan Chen, Kangdong Liu and Ziming Dong
    Citation:BMC Cancer 2020 20:43
    Content type:Correction
    Published on: 
    The original article was published in BMC Cancer 2019 19:1264
  40. Following publication of the original article [1], the authors reported an error in Fig 5 of this article, graphs presenting FCM and immunofluorescent for CD4T, CD8T and NK cell of the Control Groups (LL2, LL2...
    Authors:Hongwei Tian, Gang Shi, Guoyou Yang, Junfeng Zhang, Yiming Li, Tao Du, Jianzhou Wang, Fen Xu, Lin Cheng, Xiaomei Zhang, Lei Dai, Xiaolei Chen, Shuang Zhang, Yang Yang, Dechao Yu, Yuquan Wei…
    Citation:BMC Cancer 2020 20:42
    Content type:Correction
    Published on: 
    The original article was published in BMC Cancer 2014 14:48
  41. Optimal therapy for colorectal carcinoma (CRC), a frequently diagnosed malignancy, does not exist. Some of colicins and microcins, ribosomally synthesized peptides by gramnegative bacteria, have shown signific...
    Authors:Darina Kohoutova, Miroslava Forstlova, Paula Moravkova, Jiri Cyrany, Juraj Bosak, David Smajs, Stanislav Rejchrt and Jan Bures
    Citation:BMC Cancer 2020 20:39
    Content type:Research article
    Published on: 

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