CIENCIASMEDICASNEWS: Medical News | Medical Articles | High Throughput Multiplex Assay Identifies T-Cell Subsets, Measures T-Cell Activation and Cytokine Secretion

viernes, 28 de febrero de 2020

Medical News | Medical Articles | High Throughput Multiplex Assay Identifies T-Cell Subsets, Measures T-Cell Activation and Cytokine Secretion

	Immunology
	The latest immunology news from News Medical

Aging immune cells increase risk for macular degeneration

High Throughput Multiplex Assay Identifies T-Cell Subsets, Measures T-Cell Activation and Cytokine Secretion

Modulating the TCR signalling pathway using biologics, small molecules or genetic engineering is highly relevant to many therapeutic areas including cancer immunotherapy, adoptive cell therapy, vaccine development and autoimmune diseases. The development of these drugs and therapies requires the routine use of assays to profile T-cell function and health.

This poster describes how need for rapid monitoring of immune cell function is addressed by advanced high throughput flow cytometry.

Download The Poster

Don't Miss the Neuroimmunology Drug Development Summit

Focused on neurodegenerative diseases such as Parkinson’s, Alzheimer’s and ALS, the 2nd Annual Neuroimmunology Drug Development Summit will take place on the April 15, 2020 in Boston, MA. Listen to over 23 speakers from leading drug developers including Biogen, Alector, and Janssen.

Why full length CD20 is necessary for antibody drug development?

The new released article Structure of CD20 in complex with the therapeutic monoclonal antibody rituximab published on Science by Genentech team highlights the importance of having intact CD20 for antibody drug development. The team confirmed that the secondary ECL1/2 epitope and Fab: Fab interface contribute to the unique binding properties and high CDC activity of rituximab.

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	CRISPR-edited immune cells can be safely given to cancer patients The emergence of CRISPR-Cas9 gene-editing technology has spurred hope in both doctors and patients since it shows promise in treating a multitude of diseases, including cancer. For the first time in the United States, a team of scientists has shown that CRISPR-edited immune cells can be safely used to cancer patients.

	2019 coronavirus virus officially named COVID-19 The novel coronavirus disease, which has spread from China to 24 other countries around the globe, has received its official name – COVID-19, the World Health Organization (WHO) said.

	Immune cells count each other in order to decide whether to attack A new study published in the journal Nature Communications in February 2020 shows that immune cells consult and coordinate with each other at the site of activity to bring about a balanced but adequate reaction and stave off the threat.

	Effects of Tobacco on the Immune System Smoking is one of the leading causes of preventable deaths and illnesses within the USA, with approximately 480,000 people within the USA dying from smoking-related illnesses each year.