CIENCIASMEDICASNEWS: Separating Drugs by Chirality

martes, 13 de noviembre de 2018

Separating Drugs by Chirality

	November 13, 2018
	Biochemistry
	The latest biochemistry news from AZoNetwork

Separating Drugs by Chirality

It is always desirable to use very pure preparations that contain only one chiral isomer, or highly purified samples, when it comes to drug testing during the process of development. This increases the dependability of the results, and is essential in certain cases, such as toxicity studies.

			Biochemistry of Antibody-Antigen Interactions The interaction between antigens and antibodies, also called immunoglobulins, underpins the immune response. Antigens are typically exogenous and endogenous molecules that can engage the body’s immune system.

			Ion Channel Electrophysiology Ion channels are imperative to the normal functioning of the cell. The study of ion channels is called electrophysiology, and is described in this article.

	Overview of Strecker Amino Acid Synthesis Strecker synthesis is one of several means of producing α-amino acids. α-amino acids are molecules, which contain an amine and carboxylic group that are separated by a single carbon (the α-carbon).

	Newly developed technology can predict large volumes of unknown biochemical reactions Fujitsu Laboratories Ltd., the Insight Centre for Data Analytics, a data analytics research institution based in Ireland, and Fujitsu (Ireland) Limited today announced the development of a technology that makes it possible to predict large volumes of unknown chemical reactions, about twice as many as the conventional procedure.

	UT Southwestern biochemist receives 2019 Breakthrough Prize in Life Sciences for innate immunity discovery UT Southwestern biochemist Dr. Zhijian "James" Chen today was named winner of the prestigious 2019 Breakthrough Prize in Life Sciences for his discovery of the cGAS enzyme that launches the body's immune defense against infections and cancers.

	Histidine Metabolism Histidine is an amino acid derived from proteinaceous dairy- and meat-based products. As one of 20 amino acids, it pays an important role in the body. This article examines histidine metabolism and the consequences this has on our health.

	What is the Inflammasome? When the body becomes injured or unwell, there are many biochemical responses which are activated, including immune response, blood-clotting response, and inflammatory response. A multiprotein oligomer (a molecule consisting of many protein units), called the inflammasome, mediates this inflammatory response to injury/illness.