Plasmids Encoding and Producing Anthrax Toxin Proteins | Office of Technology Transfer, NIH

Plasmids Encoding and Producing Anthrax Toxin Proteins | Office of Technology Transfer, NIH

 Licensing Opportunity:

Improved Methods for Production of Anthrax Toxin Proteins

This scanning electron micrograph shows spores from the anthrax vaccine strain of Bacillus anthracis. These spores can live for many years, enabling the bacteria to survive in a dormant state. The spores range in size from 0.5 to 2 micrometers (millionth of a meter). Credit: CDC

Anthrax toxin and anthrax toxin fusion proteins are promising areas of research for use in anthrax vaccines and as therapeutic agents for cancer. Scientists in the NIAID Laboratory of Parasitic Diseases have developed plasmids and methods for producing anthrax proteins that are more enzymatically active, which result in higher protein yields. Read more about this exciting licensing opportunity at https://www.ott.nih.gov/technology/e-059-2008