Antiretroviral therapy (ART) suppresses HIV-1 replication but does not eradicate the virus. HIV-1 forms a reservoir that persists despite prolonged therapy and is considered the main barrier to an HIV cure. Being able to accurately measure HIV persistence in ART-treated individuals is necessary for monitoring the response to ART, as well as the effectiveness of curative interventions aimed at HIV remission. This thematic series in Retrovirology contains a collection of review articles that describe traditional and novel methods of quantitation of HIV persistence in vivo.
This collection of articles has not been sponsored and articles have undergone the journal’s standard peer review process. The Editors declare no competing interests.
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