sábado, 26 de mayo de 2018

Clinical Implication of MicroRNAs in Molecular Pathology: An Update for 2018. - PubMed - NCBI

Clinical Implication of MicroRNAs in Molecular Pathology: An Update for 2018. - PubMed - NCBI



 2018 Jun;38(2):237-251. doi: 10.1016/j.cll.2018.02.003.

Clinical Implication of MicroRNAs in Molecular Pathology: An Update for 2018.

Abstract

MicroRNAs (miRNAs) are poised to provide diagnostic, prognostic, and therapeutic targets for several diseases including malignancies for precision medicine applications. The miRNAs have immense potential in the clinical arena because they can be detected in the blood, serum, tissues (fresh and formalin-fixed paraffin-embedded), and fine-needle aspirate specimens. The most attractive feature of miRNA-based therapy is that a single miRNA could be useful for targeting multiple genes that are deregulated in cancers, which can be further investigated through systems biology and network analysis that may provide cancer-specific personalized therapy.

KEYWORDS:

Fine-needle aspirates; Pancreatic cancer; Prostate cancer; Serum; miRNAs

PMID:
 
29776629
 
DOI:
 
10.1016/j.cll.2018.02.003

No hay comentarios:

Publicar un comentario