Cancer Risk-Reducing Opportunities in Gynecologic Surgery. - PubMed - NCBI

Cancer Risk-Reducing Opportunities in Gynecologic Surgery. - PubMed - NCBI

J Minim Invasive Gynecol. 2017 Oct 30. pii: S1553-4650(17)31261-X. doi: 10.1016/j.jmig.2017.10.025. [Epub ahead of print]

Cancer Risk-Reducing Opportunities in Gynecologic Surgery.

Piszczek C1, Ma J2, Gould CH3, Tseng P2.

Author information

Abstract

This review article discusses cancer risk-reducing opportunities in gynecologic surgery. We cover strategies to reduce ovarian and uterine cancer risk by presenting general practice guidelines and expanding on the literature behind clinical decision points. We address populations of women at increased hereditary risk and those at population risk. We present discussions on the role of gynecologic surgery, specifically, risk-reducing salpingo-oophorectomy, prophylactic salpingectomy with delayed oophorectomy, concomitant hysterectomy, opportunistic salpingectomy, and bilateral tubal ligation. For clinical scenarios in which data are limited or conflicting, we detail the studies on which clinicians' decisions hinge, so that the reader can weigh the evidence themselves.

Copyright © 2017 American Association of Gynecologic Laparoscopists. Published by Elsevier Inc. All rights reserved.

KEYWORDS:

BRCA; Lynch syndrome; RRSO; hysterectomy; opportunistic; prophylactic; risk-reducing; rrSO; salpingectomy; salpingo-oophorectomy

PMID:

 

29097232

 

DOI:

 

10.1016/j.jmig.2017.10.025