BRCA-related cancer; hereditary breast and ovarian cancer

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From Tier Table Database

CDC Office of Public Health Genomics (OPHG) conducts horizon scanning (a systematic research method to find and follow novel technologies appearing in the literature) to identify and track the progress of genomic tests as they move from research into clinical and public health practice. As an aid in organizing horizon scanning results, OPHG ranks genomic tests, and family health history applications, by levels of evidence. See detail.

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Disease/Disorder	Test to be Assessed	Intended Use	Tier Classified	Detail
Hereditary breast and ovarian cancer	Family history of known breast/ovarian cancer with deleterious BRCA mutation	Risk prediction; referral to counseling for BRCA genetic testing	Tier 1
BRCA-related cancer; hereditary breast and ovarian cancer	Family history	Risk prediction for referral for BRCA genetic counseling	Tier 1

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