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Acta Neuropathologica Communications

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2. RESEARCH

   Cryptic amyloidogenic elements in mutant NEFH causing Charcot-Marie-Tooth 2 trigger aggresome formation and neuronal death

   Arnaud Jacquier, Cécile Delorme, Edwige Belotti, Raoul Juntas-Morales, Guilhem Solé, Odile Dubourg, Marianne Giroux, Claude-Alain Maurage, Valérie Castellani, Adriana Rebelo, Alexander Abrams, Stephan Züchner, Tanya Stojkovic, Laurent Schaeffer and Philippe Latour

   Published on: 14 July 2017
3. RESEARCH

   Heterogeneous ribonuclear protein E2 (hnRNP E2) is associated with TDP-43-immunoreactive neurites in Semantic Dementia but not with other TDP-43 pathological subtypes of Frontotemporal Lobar Degeneration

   Yvonne S. Davidson, Andrew C. Robinson, Louis Flood, Sara Rollinson, Bridget C. Benson, Yasmine T. Asi, Anna Richardson, Matthew Jones, Julie S. Snowden, Stuart Pickering-Brown, Tammaryn Lashley and David M. A. Mann

   Published on: 30 June 2017
4. RESEARCH

   The novel compound PBT434 prevents iron mediated neurodegeneration and alpha-synuclein toxicity in multiple models of Parkinson’s disease

   David I. Finkelstein, Jessica L. Billings, Paul A. Adlard, Scott Ayton, Amelia Sedjahtera, Colin L. Masters, Simon Wilkins, David M. Shackleford, Susan A. Charman, Wojciech Bal, Izabela A Zawisza, Ewa Kurowska, Andrew L. Gundlach, Sheri Ma, Ashley I. Bush, Dominic J. Hare…

   Published on: 28 June 2017
5. RESEARCH

   Immunoproteasome deficiency alters microglial cytokine response and improves cognitive deficits in Alzheimer’s disease-like APPPS1 mice

   Lisa K. Wagner, Kate E. Gilling, Eileen Schormann, Peter M. Kloetzel, Frank L. Heppner, Elke Krüger and Stefan Prokop

   Published on: 24 June 2017
6. RESEARCH

   Neonatal AAV delivery of alpha-synuclein induces pathology in the adult mouse brain

   Marion Delenclos, Ayman H. Faroqi, Mei Yue, Aishe Kurti, Monica Castanedes-Casey, Linda Rousseau, Virginia Phillips, Dennis W. Dickson, John D. Fryer and Pamela J. McLean

   Published on: 23 June 2017

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Featured article: Novel compound PBT434 prevents iron mediated neurodegeneration and alpha-synuclein toxicity in multiple models of Parkinson’s disease

Dr. Finkelstein et al report the preclinical characterization of PBT434, a novel quinazolinone compound bearing a moderate affinity metal-binding motif, which is in development for Parkinsonian conditions.  

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Featured article: Brain-derived exosomes from dementia with Lewy bodies propagate α-synuclein pathology

Dr. Ngolab et al investigate the role of exosomes in propogating DLB pathology, possibly through the seeding of toxic forms of α-synuclein. 

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Editors' quotes

"Acta Neuropathologica Communications is an open access, peer-reviewed online journal. Like our sister journal Acta Neuropathologica we focus on pathology and mechanisms of neurological disease. We publish high quality articles that do not require major manuscript revisions. We offer very fast turnaround times, publication of papers within two months following submission, enthusiastic editors, and a competitive article-processing charge. Try it out!"

Werner Paulus, co-Editor-in-Chief, ANC

"Acta Neuropathologica Communications is a journal for researchers working on human neurological disease and has a focus on neuropathology. However, since we believe that an interdisciplinary approach is highly valuable to advance the field, our journal is not restricted to classical neuropathological articles. Therefore, we also welcome high-quality submissions from other disciplines as long as they do ultimately aim to advance our understanding of human neurological disease. We try our best to help you with the submission process and in case of any questions do not hesitate to contact the Editors-in-Chief directly."

Johannes Attems, co-Editor-in-Chief, ANC