Details - Public Health Image Library (PHIL)

Details - Public Health Image Library (PHIL)

ID#:	16878
Description:	This illustration depicts a three-dimensional (3D)  computer-generated image of a number of rod-shaped,  drug-resistant Shigella bacteria. The artistic recreation  was based upon scanning electron micrographic imagery.  Note that the exterior of the Shigella bacterium is  fimbriated, covered by numerous thin, hair-like projections,  imparting a furry appearance.Shigella usually causes diarrhea0  (sometimes bloody), fever, and abdominal pain. Sometimes  it causes serious complications such as reactive arthritis. High-risk groups include young children, people with inadequate handwashing and hygiene habits, and men who have sex with men. Resistance to traditional first-line drugs such as ampicillin and trimethoprim-sulfamethoxazole has become so high that physicians must now rely on alternative drugs like ciprofloxacin and azithromycin to treat infections, drugs to which Shigella has shown resistance. Resistant infections can last longer than infections with susceptible bacteria (bacteria that can be treated effectively with antibiotics). Shigella causes approximately 500,000 diarrheal illnesses, 5,500 hospitalizations, and 40 deaths each year in the United States. CDC is seeing resistance to ciprofloxacin in 1.6% of the Shigella cases tested and resistance to azithromycin in approximately 3%. Because initial treatment can fail, costs are expected to be higher for resistant infections.
High Resolution:	High resolution download is not available for this image
Content Providers(s):	CDC/ Melissa Brower
Creation Date:	2013
Photo Credit:
Links:	CDC - National Center for Emerging and Zoonotic Infectious Diseases (NCEZID); Division of Foodborne, Waterborne, and Environmental Diseases (DFWED); Shigellosis: General Information CDC – CDC News Room; Digital Press Kit: i>”Untreatable: Today’s Drug-Resistant Health Threats”
Categories:	CDC Organization MeSH Anatomy Digestive System Gastrointestinal Tract Intestines Biological Sciences Biological Phenomena, Cell Phenomena, and Immunity Biological Phenomena Microbiologic Phenomena Drug Resistance, Microbial Drug Resistance, Bacterial beta-Lactam Resistance Penicillin Resistance Ampicillin Resistance Trimethoprim Resistance Chemical and Pharmacologic Phenomena Drug Resistance Drug Resistance, Microbial Drug Resistance, Bacterial beta-Lactam Resistance Penicillin Resistance Ampicillin Resistance Trimethoprim Resistance Chemicals and Drugs Carbohydrates and Hypoglycemic Agents Carbohydrates Glycosides Macrolides Erythromycin Azithromycin Heterocyclic Compounds Heterocyclic Compounds, 1-Ring Pyrimidines Trimethoprim Trimethoprim-Sulfamethoxazole Combination Heterocyclic Compounds, 2-Ring Bicyclo Compounds, Heterocyclic Penicillins Penicillin G Ampicillin Quinolines Quinolones Fluoroquinolones Ciprofloxacin Heterocyclic Compounds, Bridged-Ring Bicyclo Compounds, Heterocyclic Penicillins Penicillin G Ampicillin Organic Chemicals Amides Lactams Penicillins Penicillin G Ampicillin Sulfonamides Sulfanilamides Sulfamethoxazole Trimethoprim-Sulfamethoxazole Combination Lactones Macrolides Erythromycin Azithromycin Sulfur Compounds Sulfones Sulfonamides Sulfanilamides Sulfamethoxazole Trimethoprim-Sulfamethoxazole Combination Diseases Bacterial Infections and Mycoses Bacterial Infections Gram-Negative Bacterial Infections Enterobacteriaceae Infections Dysentery, Bacillary Digestive System Diseases Gastrointestinal Diseases Gastroenteritis Dysentery Dysentery, Bacillary Intestinal Diseases Dysentery Dysentery, Bacillary Organisms Bacteria Gram-Negative Bacteria Gram-Negative Facultatively Anaerobic Rods Enterobacteriaceae Shigella Proteobacteria Gammaproteobacteria Enterobacteriaceae Shigella
Copyright Restrictions:	None - This image is in the public domain and thus free of any copyright restrictions. As a matter of courtesy we request that the content provider be credited and notified in any public or private usage of this image.
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