PLoS Currents: Evidence on Genomic Tests - a collection by PLoS

PLoS Currents: Evidence on Genomic Tests
Rapid and open sharing of systematic reviews and summaries with researchers and the public.
Health-related applications of genomic research are increasingly available to practitioners and the public but information on their validity and utility is often fragmented. PLoS Currents: Evidence on Genomic Tests aims to provide updated summaries of available data and to highlight gaps in knowledge. All content is reviewed by a group of expert researchers.

open here to see the contents:
PLoS Currents: Evidence on Genomic Tests - a collection by PLoS

* Testing of V...
Testing of VKORC1 and CYP2C9 alleles to guide warfarin dosing
By Daurice Grossniklaus
Warfarin is an oral anticoagulant that is widely prescribed to prevent thromboembolic events in persons at increased risk....

* 2. KRAS mutatio...
KRAS mutational analysis for colorectal cancer
By Grace Wang and Robin K. Kelley
KRAS mutational analysis is a genetic test used in clinical practice for determining the status of the KRAS gene (wild typ...

* 3. CYP2D6 testi...
CYP2D6 testing to predict response to tamoxifen in women with breast cancer
By Issa Dahabreh, Teruhiko Terasawa, Peter Castaldi, and Thomas A Trikalinos
Tamoxifen, a selective estrogen receptor modulator, is the standard of care for premenopausal women with estrogen or...

* 4. Oncotype DX ...
Oncotype DX tumor gene expression profiling in stage II colon cancer
By Elizabeth M. Webber, Jennifer S. Lin and Evelyn P. Whitlock
Overall five-year survival for patients with stage-II colon cancer averages 75% after surgery alone. However, some of thes...

* 5. Tumor Gene E...
Tumor Gene Expression Profiling in Women with Breast Cancer
By Cecelia Bellcross and W. David Dotson
Differences in the expression of specific genes within breast tumors have been associated with risk of recurrence after...

* 6. PLoS Current...
PLoS Currents: Evidence on Genomic Tests – At the Crossroads of Translation
By Marta Gwinn, W. David Dotson and Muin J. Khoury
Evidence on Genomic Tests is an open access publication option for communicating high-quality, scientific information that...