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For the most recent information on genomic applications in practice and prevention, please visit the GAPP Knowledge Base


What's New
A new application has been deployed in the GAPP KB : Project Locator is an online database designed for archiving genomic translation projects including current on-going and completed projects. Users can search the database in a free text manner, and the result can be displayed in a map view or list view.

EGT Publications newly added in Evidence Aggregator

•Grace Wang, Robin K. Kelley . KRAS mutational analysis for colorectal cancer . 07/14/2010.
•Elizabeth M. Webber, Jennifer S. Lin, Evelyn P. Whitlock . Oncotype DX tumor gene expression profiling in stage II colon cancer . 06/10/2010.
•Daurice Grossniklaus . Testing of VKORC1 and CYP2C9 alleles to guide warfarin dosing . 04/29/2010.
•Issa Dahabreh, Teruhiko Terasawa, Thomas A. Trikalinos, Peter Castaldi . CYP2D6 testing to predict response to tamoxifen in women with breast cancer . 03/23/2010.


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EGAPP Recommendations newly added in Evidence Aggregator

•Recommendations from the EGAPP Working Group: can tumor gene expression profiling improve outcomes in patients with breast cancer? 01/07/2009 .
•Recommendations from the EGAPP Working Group: genetic testing strategies in newly diagnosed individuals with colorectal cancer aimed at reducing morbidity and mortality from Lynch syndrome in relatives 01/01/2009 .
•Recommendations from the EGAPP Working Group: can UGT1A1 genotyping reduce morbidity and mortality in patients with metastatic colorectal cancer treated with irinotecan? 01/01/2009 .
•Recommendations from the EGAPP Working Group: testing for cytochrome P450 polymorphisms in adults with nonpsychotic depression treated with selective serotonin reuptake inhibitors. 12/01/2007 .


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EGAPP Reviews newly added in Evidence Aggregator

•Jodi B. Segal, Daniel J. Brotman, Ashkan Emadi, Alejandro J. Necochea, Lipika Samal, Lisa M. Wilson, Matthew T. Crim, Eric B. Bass. Outcomes of Genetic Testing in Adults with a History of Venous Thromboembolism . 06/01/2009.
•Glenn E.. Palomaki, Monica R.. McClain, Stephanie Melillo, Heather L.. Hampel, Stephen N.. Thibodeau. EGAPP supplementary evidence review: DNA testing strategies aimed at reducing morbidity and mortality from Lynch syndrome . 01/01/2009.
•Linda A.. Bradley, Glenn E.. Palomaki, William D.. Dotson. Can UGT1A1 Genotyping Reduce Morbidity and Mortality in Patients with Metastatic Colorectal Cancer Treated with Irinotecan? . 01/01/2009.
•Luigi Marchionni, Renee F. Wilson, Spyridon S. Marinopoulos, Antonio C. Wolff, Giovanni Parmigiani, Eric B. Bass, Steven N. Goodman. Impact of Gene Expression Profiling Tests on Breast Cancer Outcomes . 01/01/2008.
•Peter A. Bonis, Thomas A. Trikalinos, Mei Chung, Priscilla Chew, Stanley Ip, Deirdre A. DeVine, Joseph Lau. Hereditary Nonpolyposis Colorectal Cancer: Diagnostic Strategies and Their Implications . 05/01/2007.



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EGAPP Topics newly added in GAPP Finder

• 08/20/2010: Breast cancer - Mutation detection in BRCA1 and BRCA2 genes (blood sample or oral rinse) . See detail
•08/19/2010: Heart disease - Various SNPs in the IL1 gene (cheek swab sample) . See detail
•08/10/2010: Cancer (prostate, colorectal, breast, lung, and ovarian) - Carisome platform, exosome analysis (blood plasma sample) . See detail
•08/10/2010: Mesothelioma - 4 gene ratios (tumor tissue sample) . See detail
•07/07/2010: Non-small cell lung cancer (NSCLC) - PCR-based multiple gene expression (ERCC1, TS, EGFR, RRM1) and mutation (EGRF and KRAS)(tumor sample) . See detail


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