South Asian J Cancer. 2018 Apr-Jun;7(2):106-109. doi: 10.4103/sajc.sajc_112_18.
Practical consensus recommendation on when to do BRCA testing.
Parikh PM1, Wadhwa J2, Minhas S3, Gupta A4, Mittal S5, Ranjan S6, Mehta P7, Singh R8, Kataria SP9, Salim S10, Ahmed M11, Aggarwal S3.
BRCA-mutation associated breast cancer and to future cancer risks and sensitivity to systemic therapies. Now that rapid genetic testing for BRCA1 and BRCA2 mutations is available, BRCA mutation status can be considered when making treatment and prevention decisions for BRCA testing, BRCA mutation carriers with breast cancer. Expert group used data from published literature, practical experience, and opinion of a large group of academic oncologists, to arrive at practical consensus recommendations for use by the community oncologists.
40 years; age; extended germline mutation; family history; ovarian cancer; pancreatic; paternal history; prostate