CIENCIASMEDICASNEWS: Health News and Information - News Medical - Top 10 Tips for ChIP-Seq Library Preparation

miércoles, 28 de marzo de 2018

Health News and Information - News Medical - Top 10 Tips for ChIP-Seq Library Preparation

Health News and Information - News Medical

	March 28, 2018
	Genetics
	The latest Genetics news from News Medical

Top 10 Tips for ChIP-Seq Library Preparation

With high quality library preparation being key to a successful ChIP-seq experiment, Porvair Sciences have produced a guide with illustrated tips to help improve your preparation technique.

Written by scientists with many years’ experience of ChIP assay development, the guide includes a wealth of advice, from ensuring that enzymes are stored at the appropriate temperature, to collating analytical data using the Chromatrap® ChIP-seq Data Analysis Software.

			Study uncovers new genetic cause of posterior polymorphous corneal dystrophy A new genetic cause of corneal dystrophy has been discovered with funding from Fight for Sight by researchers at UCL Institute of Ophthalmology and Moorfields Eye Hospital London, in collaboration with colleagues in the Czech Republic.

			Discovery of new ALS gene points to cytoskeleton as potential target for drug development An international team of researchers led by John Landers, PhD, at UMass Medical School, and Bryan Traynor, MD, PhD, at the National Institute on Aging at the National Institutes of Health, has identified KIF5A as a new gene associated with the development of amyotrophic lateral sclerosis.

	New computational method helps to identify tumor cell mutations with greater accuracy A new computational method developed by researchers at the New York Genome Center allows scientists to identify rare gene mutations in cancer cells with greater accuracy and sensitivity than currently available approaches.

	New test methods with less fear Many people shy away from going to the doctor's, because they are afraid of unpleasant truths, such as the diagnosis of a disease. Researchers of Karlsruhe Institute of Technology (KIT) and Tilburg University, Netherlands, have developed a method to overcome this fear, which is reported in the journal Management Science.

	New study identifies key cellular mechanisms behind vascular aging in mice We are as old as our arteries, the adage goes, so could reversing the aging of blood vessels hold the key to restoring youthful vitality? The answer appears to be yes, at least in mice, according to a new study led by investigators at Harvard Medical School.

	Discovery of genes could lead to development of novel therapies for EBV-related cancers VCU Massey Cancer Center researchers have identified two genes that are responsible for governing the replication of the Epstein-Barr virus, an infection that drives the growth of several types of cancer.

	Researchers uncover cause of rare childhood neurodegenerative disease Neurology researchers investigating a rare but devastating neurological regression in infants have discovered the cause: gene mutations that severely disrupt crucial functions in mitochondria, the energy-producing structures within cells.