Breast cancer in young women: do BRCA1 or BRCA2 mutations matter? - The Lancet Oncology

Breast cancer in young women: do BRCA1 or BRCA2 mutations matter? - The Lancet Oncology

Breast cancer in young women: do BRCA1 or BRCA2 mutations matter?

Peter A FaschingEmail the author Peter A Fasching

Published: 11 January 2018

Open Access

PlumX Metrics

DOI: http://dx.doi.org/10.1016/S1470-2045(18)30008-1

 |

Article Info

• Summary

• Full Text
• Tables and Figures
• References

Young women with breast cancer have always caught the attention of both clinicians and researchers, despite this group being a rarity. Several factors distinguish the biology of both breast cancer in young patients and the patients themselves from that of tumours and patients who are diagnosed later in life. Additionally, the cancers might be associated with a previous pregnancy or have a pathogenesis that is based on a genetic predisposition; some data even imply that both cancers associated with a previous pregnancy and a genetic predisposition to cancer might be directly connected.