domingo, 28 de enero de 2018

Cancer-Related Genetic Testing and Personalized Medicine for Adolescents: A Narrative Review of Impact and Understanding. - PubMed - NCBI

Cancer-Related Genetic Testing and Personalized Medicine for Adolescents: A Narrative Review of Impact and Understanding. - PubMed - NCBI



 2018 Jan 16. doi: 10.1089/jayao.2017.0102. [Epub ahead of print]

Cancer-Related Genetic Testing and Personalized Medicine for Adolescents: A Narrative Review of Impact and Understanding.

Abstract

Genetic testing is becoming increasingly available for adolescents who are undergoing cancer treatment or at risk of cancer predisposition syndromes. With this narrative review, we aimed to synthesize the evidence on psychosocial outcomes and adolescents' understanding of genetic testing-thus far, an underresearched topic. Both psychological benefits and harms of predictive testing were reported in adolescents from high-risk families. Harms were mainly related to cancer-specific distress and increased worries. Findings on genetic understanding were sparse. Future studies should focus on psychosocial outcomes and adolescents' understanding undergoing genetic testing and enabling access to genetic counseling pre-testing and post-testing.

KEYWORDS:

adolescent; narrative review; oncology; personalized medicine; predictive genetic testing; psychosocial

PMID:
 
29336661
 
DOI:
 
10.1089/jayao.2017.0102

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