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BMC Structural Biology

Featured article: A comparative analysis of the foamy and ortho virus capsid structures reveals an ancient domain duplication

Taylor, Stoye and Taylor applied protein structure comparison methods to resolve the ambiguous relationship between Spumaretrovirinae (foamy viruses) and the Orthoretrovirinae (e.g. HIV). Their results show the relationship conforms to a simple linear correspondence, with similarities suggesting the viral capsids originated from a common ancestor with a double domain structure.

The comparison methodology used in this article demonstrates an effective general approach to problems where the components have a high intrinsic level of similarity.

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2. RESEARCH ARTICLE

   Rosetta Broker for membrane protein structure prediction: concentrative nucleoside transporter 3 and corticotropin-releasing factor receptor 1 test cases

   Dorota Latek

   Published on: 3 August 2017
3. RESEARCH ARTICLE

   A computational assessment of pH-dependent differential interaction of T7 lysozyme with T7 RNA polymerase

   Subhomoi Borkotoky and Ayaluru Murali

   Published on: 25 May 2017
4. RESEARCH ARTICLE

   Destabilization of the TWIST1/E12 complex dimerization following the R154P point-mutation of TWIST1: an in silico approach

   Charlotte Bouard, Raphael Terreux, Agnès Tissier, Laurent Jacqueroud, Arnaud Vigneron, Stéphane Ansieau, Alain Puisieux and Léa Payen

   Published on: 18 May 2017
5. RESEARCH ARTICLE

   Molecular dynamics simulation of the opposite-base preference and interactions in the active site of formamidopyrimidine-DNA glycosylase

   Alexander V. Popov, Anton V. Endutkin, Yuri N. Vorobjev and Dmitry O. Zharkov

   Published on: 8 May 2017
6. DATABASE

   REFOLDdb: a new and sustainable gateway to experimental protocols for protein refolding

   Hisashi Mizutani, Hideaki Sugawara, Ashley M. Buckle, Takeshi Sangawa, Ken-ichi Miyazono, Jun Ohtsuka, Koji Nagata, Tomoki Shojima, Shohei Nosaki, Yuqun Xu, Delong Wang, Xiao Hu, Masaru Tanokura and Kei Yura

   Published on: 24 April 2017

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