miércoles, 15 de agosto de 2012

National Guideline Clearinghouse | The role of cytotoxic therapy with hematopoietic stem cell transplantation in the treatment of adult acute lymphoblastic leukemia: update of the 2006 evidence-based review.

full-text:
National Guideline Clearinghouse | The role of cytotoxic therapy with hematopoietic stem cell transplantation in the treatment of adult acute lymphoblastic leukemia: update of the 2006 evidence-based review.



Guideline Title
The role of cytotoxic therapy with hematopoietic stem cell transplantation in the treatment of adult acute lymphoblastic leukemia: update of the 2006 evidence-based review.
 
 
Bibliographic Source(s)
ASBMT position statement. The role of cytotoxic therapy with hematopoietic stem cell transplantation in the treatment of adult acute lymphoblastic leukemia: update of the 2006 evidence-based review. Biol Blood Marrow Transplant 2012 Jan;18(1):16-7. [2 references] PubMed External Web Site Policy
Oliansky DM, Larson RA, Weisdorf D, Dillon H, Ratko TA, Wall D, McCarthy PL Jr, Hahn T. The role of cytotoxic therapy with hematopoietic stem cell transplantation in the treatment of adult acute lymphoblastic leukemia: update of the 2006 evidence-based review. Biol Blood Marrow Transplant 2012 Jan;18(1):18-36.e6. [68 references] PubMed External Web Site Policy
 
 
Guideline Status
This is the current release of the guideline.
This guideline updates a previous version:
ASBMT Executive Committee. The role of cytotoxic therapy with hematopoietic stem cell transplantation in the treatment of acute lymphoblastic leukemia in adults. Biol Blood Marrow Transplant 2006 Mar;12(3):368-9. [3 references]
Hahn T, Wall D, Camitta B, Davies S, Dillon H, Gaynon P, Larson RA, Parsons S, Seidenfeld J, Weisdorf D, McCarthy PL Jr. The role of cytotoxic therapy with hematopoietic stem cell transplantation in the therapy of acute lymphoblastic leukemia in adults: an evidence-based review. Biol Blood Marrow Transplant 2006 Jan;12(1):1-30. [83 references]



2012 Jan;18(1):16-7. Epub 2011 Sep 29.

The role of cytotoxic therapy with hematopoietic stem cell transplantation in the treatment of adult acute lymphoblastic leukemia: update of the 2006 evidence-based review.

Source

Roswell Park Cancer Institute, Buffalo, NY, USA.

2012 Jan;18(1):18-36.e6. Epub 2011 Jul 29.

The role of cytotoxic therapy with hematopoietic stem cell transplantation in the treatment of adult acute lymphoblastic leukemia: update of the 2006 evidence-based review.

Source

Roswell Park Cancer Institute, Buffalo, New York 14263, USA.

Abstract

Clinical research published since the first evidence-based review on the role of hematopoietic stem cell transplantation (SCT) in the treatment of acute lymphoblastic leukemia (ALL) in adults is presented and critically evaluated in this update. Treatment recommendations changed or modified based on new evidence include: (1) myeloablative allogeneic SCT is an appropriate treatment for adult (<35 a="a" absence="absence" adult="adult" after="after" all="all" allogeneic="allogeneic" an="an" and="and" appropriate="appropriate" are="are" areas="areas" autologous="autologous" based="based" be="be" before="before" blood="blood" but="but" by="by" chemotherapy="chemotherapy" complete="complete" conditioning="conditioning" consider="consider" cord="cord" disease="disease" donor="donor" evidence="evidence" first="first" for="for" greater="greater" groups="groups" high="high" hla="hla" identified="identified" imatinib="imatinib" in="in" include:="include:" is="is" it="it" may="may" myeloablative="myeloablative" needed="needed" new="new" no="no" of="of" on="on" or="or" outcomes.="outcomes." outcomes="outcomes" over="over" patients="patients" ph="ph" presented="presented" produce="produce" rate="rate" recommendations="recommendations" recommended="recommended" reduced-intensity="reduced-intensity" regimens.="regimens." relapse="relapse" related="related" remission="remission" research="research" results="results" review.="review." risk="risk" sct.="sct." sct="sct" second="second" significantly="significantly" similar="similar" strengthened="strengthened" suitable="suitable" superior="superior" survival="survival" the="the" therapy="therapy" there="there" to="to" transplantation="transplantation" treatment="treatment" unchanged="unchanged" unrelated="unrelated" well-matched="well-matched" were="were" with="with" years="years" yields="yields">Copyright © 2012 American Society for Blood and Marrow Transplantation. Published by Elsevier Inc. All rights reserved.

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