viernes, 19 de enero de 2024
She’s hellbent on solving the organ shortage with ‘designer pigs.’ Just don’t keep her waiting Sharon Begley By Sharon Begley
https://www.statnews.com/2017/04/06/crispr-pig-organs-transplant-luhan-yang/?utm_campaign=morning_rounds&utm_medium=email&_hsmi=290577490&_hsenc=p2ANqtz-88p43AuI1eKGqEOZFyq1XvWFhsQo200SBSn03L5us-U5OyuODkTqUdK-FSVJCAKmHMXU4JGYw2bCgNmUFO1pgzwl5Fqw&utm_content=290577490&utm_source=hs_email
When I hear about eGenesis, a pioneer in xenotransplantation deploying CRISPR to edit viruses out of pig organs, I think of its mission to solve the shortage of organs. That’s still its goal, but now the company is working with researchers at Penn Medicine to use human-friendly pig organs as a bridge for critically ill patients waiting to get better or to receive a human transplant. The technique is called extracorporeal perfusion and it circulates a patient’s blood through a genetically engineered pig organ kept alive in an incubator. Yesterday researchers said the procedure passed its first test in a brain-dead human.
STAT’s Megan Molteni describes it as “kind of like dialysis, except the guts of the machine are literal guts, from a pig.” Mike Curtis, eGenesis's CEO, told her “it’s not xenotransplant, but it’s a technology and a product that can fulfill a huge unmet need.” Caveat: Data from this experiment have not been published or made available as a preprint. Read more.
https://www.statnews.com/2024/01/18/egenesis-crispr-pig-liver-tested-in-brain-dead-patient/?utm_campaign=morning_rounds&utm_medium=email&_hsmi=290577490&_hsenc=p2ANqtz-8JHU0UepejBlmeMYPBy9TzCRKn44trGmyRYIliNdWlKi5NUP-4GHIh-MwRpLsP1nUnDsB6vRYLvCGYlMi2CLsttB4j6A&utm_content=290577490&utm_source=hs_email
Hypothermia and frostbite: Easier to develop than you might think Tips to prevent and treat cold-related health problems
https://magazine.medlineplus.gov/article/hypothermia-and-frostbite-easier-to-develop-than-you-might-think?utm_medium=email&utm_source=govdelivery
What is hypothermia? Cold temperatures can cause hypothermia, which occurs when your body temperature drops below 95 degrees Fahrenheit (35 degrees Celsius). Hypothermia can lead to health problems like heart attacks, kidney problems, liver damage, or death. Warning signs include: Shivering Exhaustion Confusion Memory loss Fumbling hands Infants and older adults are especially at risk for hypothermia because they have a harder time regulating their body temperature. Medical conditions
Join Us at the International Congress on Integrative Medicine and Health in Cleveland January 18, 2024
I hope to see you at the in-person 2024 International Congress on Integrative Medicine and Health (ICIMH) in Cleveland, Ohio, from April 9 through April 13, 2024.
https://www.nccih.nih.gov/research/blog/join-us-at-the-international-congress-on-integrative-medicine-and-health-in-cleveland?nav=govd
I hope to see you at the in-person 2024 International Congress on Integrative Medicine and Health (ICIMH) in Cleveland, Ohio, from April 9 through April 13, 2024. As a member of the program committee for the Congress, I can tell you that we have a wonderful agenda planned, with an emphasis on one of the major challenges for our field—moving integrative health care strategies into mainstream care.
ICIMH, which is convened by the Academic Consortium for Integrative Medicine and Health, brings together leading figures from different fields to showcase recent scientific advancements in integrative medicine and health. It provides great opportunities for cross-disciplinary networking, along with an extensive schedule of presentations on original research, educational innovations, clinical delivery models, and policy challenges. Be sure to register by March 8, 2024, to avoid late fees.
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