Does High-Dose Vitamin D3 Supplementation Improve CRC Survival? Edited by Katie Lennon

https://www.medscape.com/viewarticle/does-high-dose-vitamin-d3-supplementation-improve-crc-2026a1000qib High-dose vitamin D3 supplementation added to standard chemotherapy plus bevacizumab does not improve progression-free survival (PFS) compared with standard-dose vitamin D3 in patients with previously untreated metastatic colorectal cancer (mCRC). Among 455 randomized patients, median PFS was 11.8 months in the high-dose group vs 10.3 months in the standard-dose group, with no significant differences in objective response rates or overall survival.