Ketamine boosts neuroplasticity through microglia in female brains

https://www.news-medical.net/news/20260731/Ketamine-boosts-neuroplasticity-through-microglia-in-female-brains.aspx Doctors use ketamine on patients as general anesthesia before surgery. They also prescribe it in low doses for pain management, and more recently, it's been used for treatment-resistant depression where other drugs have failed. It works by dampening communication between brain cells. But a new study reveals that its effects on the brain are different in male and female mice. This insight-if reproduced in humans-could change the way we test the efficacy of drugs and unlock better treatments for depression.