ER-Positive/HER2-Negative Metastatic Breast Cancer: Navigating Endocrine Resistance and Expanding Treatment Options (+... videos +++++)

New Resources Available: ER+/HER2−- Metastatic Breast Cancer: Navigating Endocrine Resistance and Expanding Treatment Options ER-Positive/HER2-Negative Metastatic Breast Cancer: Navigating Endocrine Resistance and Expanding Treatment Options Endocrine therapy remains the cornerstone of treatment for ER-positive/HER2-negative metastatic breast cancer, yet both intrinsic and acquired resistance ultimately limit its long-term success. Resistance arises through diverse mechanisms—including activating ESR1... https://www.medscape.org/advances/oral-serds-2025a1000o90?src=mkmcmr_driv_32025_mscpedu_437674.35_ace_final&uac=148436CN Endocrine Therapies in ER-Positive/HER2-Negative MBC: Understanding Their Benefits and Limitations to Optimize Treatment Selection Authors: Joyce A. O’Shaughnessy, MD; Aditya Bardia, MD, MPH, FASCO https://www.medscape.org/viewarticle/1003008?src=mkmcmr_driv_32025_mscpedu_437674.35_ace_final&uac=148436CN Communicating to Enhance Care Through Data and Patient Experience: ER-Positive/HER2-Negative Metastatic Breast Cancer Edition Authors: Kelly Shanahan, MD; Sara Tolaney, MD, MPH; Virginia Kaklamani, MD, DSc; Sarah R. Donahue, MPH, NP, AOCNP; Abigail Shockley, PharmD, BCOP https://www.medscape.org/viewarticle/communicating-enhance-care-through-data-and-patient-2025a1000uqi?page=1&src=mkmcmr_driv_32025_mscpedu_437674.35_ace_final&uac=148436CN Enhancing Clinical Understanding of Oral SERD-Based Therapies for Patients With ER-Positive/HER2-Negative MBC Authors: Nadia Harbeck, MD, PhD; Virginia Kaklamani, MD, DSc; Gregory Vidal, MD, PhD https://www.medscape.org/viewarticle/enhancing-clinical-understanding-oral-serd-based-therapies-2026a1000a46?page=1&src=mkmcmr_driv_32025_mscpedu_437674.35_ace_final&uac=148436CN Current and Future Oral SERD Strategies in the Management of ER-Positive/HER2-Negative MBC: Analyzing the Clinical Data Authors: Komal Jhaveri, MD, FACP, FASCO; Shaheenah Dawood, MD, MPH https://www.medscape.org/viewarticle/current-and-future-oral-serd-strategies-management-er-2026a100022b?page=1&src=mkmcmr_driv_32025_mscpedu_437674.35_ace_final&uac=148436CN Patients Progressing on an AI ± CDK4/6 Inhibitors: From Biomarkers to Treatment Strategies Authors: Manali Bhave, MD; Nadia Harbeck, MD, PhD https://www.medscape.org/viewarticle/patients-progressing-ai-cdk4-6-inhibitors-biomarkers-2025a1000wtp?page=1&src=mkmcmr_driv_32025_mscpedu_437674.35_ace_final&uac=148436CN