Depression
Also called: Clinical depression, Dysthymic disorder, Major depressive disorder, Unipolar depressionWomen and Depression
Being sad is a normal reaction to difficult times in life. But usually, the sadness goes away with a little time. Depression is different — it is a medical condition that may cause severe symptoms that can affect how you feel, think, and handle daily activities like sleeping, eating, or working. Certain types of depression are unique to women, likely due to certain biological, hormonal, and social factors.
National Institutes of Health
The primary NIH organization for research on Depression is theNational Institute of Mental Health
Other Languages
Find health information in languages other than English on Depression
Disclaimers
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Summary
Depression is a serious medical illness. It's more than just a feeling of being sad or "blue" for a few days. If you are one of the more than 19 million teens and adults in the United States who have depression, the feelings do not go away. They persist and interfere with your everyday life. Symptoms can include
- Feeling sad or "empty"
- Loss of interest in favorite activities
- Overeating, or not wanting to eat at all
- Not being able to sleep, or sleeping too much
- Feeling very tired
- Feeling hopeless, irritable, anxious, or guilty
- Aches or pains, headaches, cramps, or digestive problems
- Thoughts of death or suicide
Depression is a disorder of the brain. There are a variety of causes, including genetic, biological, environmental, and psychological factors. Depression can happen at any age, but it often begins in teens and young adults. It is much more common in women. Women can also get postpartum depression after the birth of a baby. Some people get seasonal affective disorder in the winter. Depression is one part of bipolar disorder.
There are effective treatments for depression, including antidepressants, talk therapy, or both.
NIH: National Institute of Mental Health
Start Here
- Depression (National Institute of Mental Health)
- Depression (Major Depressive Disorder) (Mayo Foundation for Medical Education and Research)
- Depression: What You Need to Know (National Institute of Mental Health)Also in Spanish
- Help With Depression (American Psychiatric Association)
Symptoms
- Signs and Symptoms of Mood Disorders (Depression and Bipolar Support Alliance)
Diagnosis and Tests
- Depression Screening (National Library of Medicine)Also in Spanish
Treatments and Therapies
- Antidepressants: MedlinePlus Health Topic (National Library of Medicine)Also in Spanish
- Antipsychotic drugs a last resort for these 5 conditions (ADHD, Anxiety, Depression, Insomnia and PTSD) (Consumers Union of U.S.)
- Brain Stimulation Therapies (National Institute of Mental Health)
- Depression Treatment (Centers for Disease Control and Prevention)
- Psychotherapies (National Institute of Mental Health)
- St. John's Wort and Depression (National Center for Complementary and Integrative Health)
- Therapy and Counseling (American Academy of Family Physicians)Also in Spanish
- Time to Talk: 5 Things to Know about St. John's Wort and Depression (National Center for Complementary and Integrative Health)
Living With
- Depression and Anxiety: Exercise Eases Symptoms(Mayo Foundation for Medical Education and Research)Also in Spanish
- Depression: Supporting a Family Member or Friend(Mayo Foundation for Medical Education and Research)Also in Spanish
Related Issues
- Alzheimer's or Depression: Could It Be Both? (Mayo Foundation for Medical Education and Research)Also in Spanish
- Chronic Illness & Mental Health (National Institute of Mental Health)Also in Spanish
- Coping with Unexpected Events: Depression and Trauma (Depression and Bipolar Support Alliance)
- Depression and African Americans (Mental Health America)
- Depression and Anxiety in Migraine Patients (American Migraine Foundation)
- Depression and Suicide Risk (American Association of Suicidology) - PDF
Specifics
- Atypical Depression (Mayo Foundation for Medical Education and Research)Also in Spanish
- Depression (PDQ) (National Cancer Institute)Also in Spanish
- Depression and Alzheimer's Disease (American Academy of Family Physicians)Also in Spanish
- Depression and Caregiving (Family Caregiver Alliance)Also in Spanish
- Depression in the Workplace (Mental Health America)
- Lupus and Depression: Know the Signs and How to Get Help (Lupus Foundation of America)
- Persistent Depressive Disorder (PDD) formerly Dysthymic Disorder(American Academy of Family Physicians)
- Treatment-Resistant Depression (Mayo Foundation for Medical Education and Research)Also in Spanish
- What Does the Term "Clinical Depression" Mean?(Mayo Foundation for Medical Education and Research)
Genetics
- Genetics Home Reference: depression (National Library of Medicine)
Health Check Tools
- Depression Screening: Questionnaire (Department of Veterans Affairs)
Statistics and Research
- Depression in Older Adults (Mental Health America)
- Major Depression Among Adults (National Institute of Mental Health)
- Physical Activity May Lessen Depression Symptoms (National Institutes of Health)
Clinical Trials
- ClinicalTrials.gov: Depression (National Institutes of Health)
- ClinicalTrials.gov: Dysthymic Disorder (National Institutes of Health)
Journal ArticlesReferences and abstracts from MEDLINE/PubMed (National Library of Medicine)
Find an Expert
- American Psychiatric Association
- Behavioral Health and Substance Abuse Treatment Services Locator(Substance Abuse and Mental Health Services Administration)
- Find Your Local NAMI (NAMI)
- Help for Mental Illnesses (National Institute of Mental Health)
- National Institute of Mental Health
- Psychologist Locator (American Psychological Association)
Children
- Sadness and Depression (Nemours Foundation)Also in Spanish
- Taking Your Child to a Therapist (Nemours Foundation)Also in Spanish
Men
- Male Depression: Understanding the Issues (Mayo Foundation for Medical Education and Research)Also in Spanish
- Men and Depression (National Institute of Mental Health)Also in Spanish
Women
- Depression (Department of Health and Human Services, Office on Women's Health)Also in Spanish
- Depression and Pregnancy (Organization of Teratology Information Specialists) - PDFAlso in Spanish
- Depression in Women: 5 Things You Should Know (National Institute of Mental Health)
- Depression in Women: Understanding the Gender Gap(Mayo Foundation for Medical Education and Research)Also in Spanish
Older Adults
- Older Adults and Depression (National Institute of Mental Health)Also in Spanish
Patient Handouts
- Depression (Medical Encyclopedia)Also in Spanish
- Depression - elderly (Medical Encyclopedia)Also in Spanish
- Depression - stopping your medicines (Medical Encyclopedia)Also in Spanish
- Dysthymia (Medical Encyclopedia)Also in Spanish
- Heart disease and depression (Medical Encyclopedia)Also in Spanish
- Learning about depression (Medical Encyclopedia)Also in Spanish
- Major depression (Medical Encyclopedia)Also in Spanish
- Major depression with psychotic features (Medical Encyclopedia)Also in Spanish
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