Findings from a recent preliminary trial, published in The Journal of Pediatrics, suggest that the probiotic Lactobacillus reuteri strain DSM 17938 may be safe for use in infants with colic. These results, however, must be interpreted with caution because of the small study size. The study, funded in part by NCCIH, was led by researchers from the University of Texas Health Science Center at Houston and Louisiana State University Health Sciences Center.
Colic is a condition that results in inexplicable and severe crying in otherwise healthy newborns. The causes of this condition are unknown, but researchers suspect the gut is involved because symptoms usually worsen after feedings. An emerging body of evidence suggests that colicky infants may have an abnormal microbiome (community of microorganisms) in the gut, which may lead to inflammation, causing discomfort.