CIENCIASMEDICASNEWS: Pulmonology - Nov 14, 2017 Edition

miércoles, 15 de noviembre de 2017

Pulmonology - Nov 14, 2017 Edition

	November 14, 2017
	Pulmonology
	The latest pulmonology news from News Medical

	Experts highlight importance of early lung cancer screening Lung cancer is the second most common cancer in both men and women, and is by far the leading cause of cancer death among both men and women. In 2017, the American Cancer Society estimates more than 200,000 new cases of lung cancer will be diagnosed in the United States, with more than 150,000 deaths.

	An alternative approach to augmenting the effect of antibiotics in chronic CF lung infections There are about 77,000 people known to have cystic fibrosis. That's from the various cystic fibrosis registries available globally. The World Health Organization suggests that this number may be low, because there's no reporting on cystic fibrosis from the developing world. The accepted number, at the moment, is about 80,000. That's the one that is used for most of the work that's being done on cystic fibrosis.

			Combination therapy with azithromycin found to be unnecessary in most children with pneumonia A combination of two antibiotics is often prescribed to treat community-acquired pneumonia in children but a JAMA Pediatrics study is now showing that using just one of the two has the same benefit to patients in most cases.

			Hot flashes, night sweats in middle-aged women may be linked to high risk of obstructive sleep apnea In a new study published today in Menopause, researchers have found that the hot flashes and night sweats faced by upward of 80 percent of middle-aged women may be linked to an increased risk of obstructive sleep apnea.

			Quorum sensing data presented at the North American Cystic Fibrosis Conference by Neem Biotech Neem Biotech, the Welsh-based fundamental Research and Development arm of the Zaluvida group of life science companies, was pleased to present the work into development of a novel mode of action as an adjunct to existing antibiotics at the North American Cystic Fibrosis Conference Indiana, USA from 2nd November 2017 to 4th of November 2017.

			Researchers identify neural circuitry responsible for rousing the brain during sleep apnea A common and potentially serious sleep disorder, obstructive sleep apnea affects at least one-quarter of U.S. adults and is linked to increased risk of diabetes, obesity and cardiovascular disease. In a paper published today in the journal Neuron, researchers at Beth Israel Deaconess Medical Center identified specific neural circuitry responsible for rousing the brain of mice in simulated apnea conditions.

			Vaccines in the Aging Population The World Health Organisation marked World Pneumonia Day on November 12th to promote interventions to protect against, prevent and treat pneumonia. The condition is a worldwide killer affecting people of all ages, however the ‘aging population’ is at an increased risk.

	Breastfeeding may increase hay fever and eczema risk, but does not have clear effect on asthma The effect of breastfeeding on the risk of developing asthma and allergy has been debated for a long time. In a recent study, Uppsala University researchers show that breastfeeding might in fact increase the risk of developing hay fever and eczema, while not having any clear effect on the risk of asthma.

	Severe hot flashes in midlife linked to higher risk for obstructive sleep apnea Many menopausal women complain about poor sleep. Should the problem be blamed simply on menopause or on a more serious underlying sleep disorder such as obstructive sleep apnea (OSA)? What, if any, is the connection between hot flashes, which can also lead to cardiovascular risk, and OSA? New study results being published online today in Menopause, the journal of The North American Menopause Society, examine that relationship.

	OSA may put elderly people at increased risk of developing Alzheimer's disease Obstructive sleep apnea (OSA) may put elderly people at greater risk of developing Alzheimer's disease (AD), according to new research published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

	FDG PET/CT imaging shows correlation between amount of cfDNA and cancer aggressiveness Italian researchers have demonstrated a better way of determining the aggressiveness of tumors in patients with advanced non-small cell lung cancer (NSCLC).

	Experts drive Neem Biotech’s efforts to counter effects of antimicrobial resistance on treatment of lung infections Neem Biotech, the Welsh-based fundamental Research and Development arm of the Zaluvida group of life science companies, is pleased to present an interview with two thought leaders in the field of bacterially-caused chronic lung infections.

	Elevated levels of chronic stress hormones may promote EGFR inhibitor resistance in NSCLC patients Elevated levels of chronic stress hormones, such as those produced by psychological distress, may promote resistance to drugs commonly used to treat lung cancer patients with EGFR mutations, according to new research from The University of Texas MD Anderson Cancer Center.

	Air pollution linked to mortality from kidney, bladder and colorectal cancer Air pollution is classified as carcinogenic to humans given its association with lung cancer, but there is little evidence for its association with cancer at other body sites.

	JTFPP guidelines offer practical advice on medications to treat seasonal allergic rhinitis In a newly updated clinical practice guideline, published in Annals of Allergy, Asthma, and Immunology, allergists offer practical advice on the best types and amounts of medications to treat seasonal allergic rhinitis. Annals is the scientific publication of the American College of Allergy, Asthma, and Immunology.

	Using biologics during pregnancy may not raise infant's risk for opportunistic infections Using a biologic therapy to manage rheumatoid arthritis may not significantly increase an infant's risk for developing opportunistic infections like pneumonia, meningitis, and tuberculosis, according to new research findings presented this week at the 2017 ACR/ARHP Annual Meeting in San Diego.

	Study shows that HPV vaccine also prevents recurrent respiratory papillomatosis in children The vaccine that protects against cancer-causing types of human papillomavirus (HPV) also prevents an uncommon but incurable childhood respiratory disease, according to a new study published in The Journal of Infectious Diseases.

	Smoking and Effects on the Stomach Smoking may affect the entire body, increasing the chances of developing several life-threatening ailments such as heart disease, emphysema, and lung cancer. Smoking leads to numerous diseases and several types of cancers of the digestive system, such as stomach cancer, bowel cancer and colon polyps. The diseases caused as a result of smoking leads to the deaths of about 400,000 Americans annually.

	Smoking and alcohol consumption in OECD countries – country breakdown Both smoking and alcohol consumption have been linked to several deadly diseases include coronary heart disease, ischemic heart disease, strokes, diabetes, several cancers, liver diseases etc. Smoking is directly associated with lung diseases such as asthma, chronic obstructive pulmonary disease (COPD).

	Blood biomarkers appear to be early-warning signal for lung problems in WTC-exposed firefighters Blood biomarkers appear to be an early-warning signal for the accelerated loss of lung function and airway obstruction in firefighters who responded to the World Trade Center disaster, according to new research published online in the Annals of the American Thoracic Society.

	Pneuma Respiratory's digital soft mist device can deliver different types of medicines to the lungs Pneuma Respiratory has developed the first fully digital, soft mist inhaler. Early clinical studies have shown that the platform can effectively deliver a number of different types of medicines to the lungs.

	Early-warning blood biomarkers identified for lung damage Blood biomarkers that predict accelerated loss of lung function have been identified in a study of fire-fighters who worked in the aftermath of the World Trade Center disaster.

	New category of immunotherapy appears safe to use in patients with both cancer and HIV A new category of immunotherapies called checkpoint inhibitors that has been highly effective against many different cancers appears safe to use in patients with both advanced malignancies and HIV, a population excluded from earlier trials of such therapies, according to an early-phase trial.

	Common antidepressants may not work for depressed patients with chronic kidney disease Scientists are finding more evidence that commonly prescribed antidepressants aren't effective in people battling both depression and a chronic medical disease, raising a critical question of whether doctors should enact widespread changes in how they treat millions of depressed Americans.

	Novel approach could help predict how well patients respond to cancer treatment A novel approach developed by researchers from the University of Leicester and the MRC Toxicology Unit could help to predict how well patients respond to drugs designed to fight various forms of cancer.

	Novel mathematical model can predict how cancer patient will benefit from immunotherapies Researchers at the Icahn School of Medicine at Mount Sinai have created the first mathematical model that can predict how a cancer patient will benefit from certain immunotherapies, according to a study published in Nature.

	New PEth test could accurately identify alcohol misuse in critically ill patients A simple blood test for a compound called PEth can accurately identify critically ill hospital patients who misuse alcohol, a study has found.

	Leading organizations call for responsible use of antibiotics to combat rising drug resistance In the lead-up to World Antibiotic Awareness Week (13-19 November 2017), the Food and Agriculture Organization of the United Nations, the World Health Organization and the World Organisation for Animal Health are together calling for responsible use of antibiotics in humans and animals to reduce the emergence of antibiotic resistance.