Primary Immunodeficiency Disorders
Primary Immunodeficiency Disorders: Public Health and Genomic Insights- June 25, 2015
CDC and Related Info
Update on vaccine-derived polioviruses — worldwide, January 2014–March 2015
MMWR June 19, 2015 / 64(23);640-646
MMWR June 19, 2015 / 64(23);640-646
Primary immunodeficiencies with elevated IgE.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vtDSGMI-yEezW7P4xVGYYkjlbjLLdcDfSqDf3al8Q8qcsxBiogiQj8SslVDfzwez2cIM6UbpbkGJDzq1MNEd92BUmj0NVtjfabKOQqWNS3ENvRw7ClRekD=s0-d)
Mogensen TH et al. Int. Rev. Immunol. 2015 May 13.
Mogensen TH et al. Int. Rev. Immunol. 2015 May 13.
Inherited and acquired immunodeficiencies underlying tuberculosis in childhood.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vtDSGMI-yEezW7P4xVGYYkjlbjLLdcDfSqDf3al8Q8qcsxBiogiQj8SslVDfzwez2cIM6UbpbkGJDzq1MNEd92BUmj0NVtjfabKOQqWNS3ENvRw7ClRekD=s0-d)
Boisson-Dupuis S et al. Immunol. Rev. 2015 Mar (1) 103-20
Boisson-Dupuis S et al. Immunol. Rev. 2015 Mar (1) 103-20
Diagnosing primary immunodeficiency: a practical approach for the non-immunologist.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vtDSGMI-yEezW7P4xVGYYkjlbjLLdcDfSqDf3al8Q8qcsxBiogiQj8SslVDfzwez2cIM6UbpbkGJDzq1MNEd92BUmj0NVtjfabKOQqWNS3ENvRw7ClRekD=s0-d)
Lehman H et al. Curr Med Res Opin 2015 Apr (4) 697-706
Lehman H et al. Curr Med Res Opin 2015 Apr (4) 697-706
Mendelian susceptibility to mycobacterial disease: genetic, immunological, and clinical features of inborn errors of IFN-γ immunity.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vtDSGMI-yEezW7P4xVGYYkjlbjLLdcDfSqDf3al8Q8qcsxBiogiQj8SslVDfzwez2cIM6UbpbkGJDzq1MNEd92BUmj0NVtjfabKOQqWNS3ENvRw7ClRekD=s0-d)
Bustamante J et al. Semin. Immunol. 2014 Dec (6) 454-70
Bustamante J et al. Semin. Immunol. 2014 Dec (6) 454-70
Comparison of diagnostic criteria for common variable immunodeficiency disorder.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vtDSGMI-yEezW7P4xVGYYkjlbjLLdcDfSqDf3al8Q8qcsxBiogiQj8SslVDfzwez2cIM6UbpbkGJDzq1MNEd92BUmj0NVtjfabKOQqWNS3ENvRw7ClRekD=s0-d)
Ameratunga R et al. Front Immunol 2014 415
Ameratunga R et al. Front Immunol 2014 415
A clinical and laboratory approach to the evaluation of innate immunity in pediatric CVID patients.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vtDSGMI-yEezW7P4xVGYYkjlbjLLdcDfSqDf3al8Q8qcsxBiogiQj8SslVDfzwez2cIM6UbpbkGJDzq1MNEd92BUmj0NVtjfabKOQqWNS3ENvRw7ClRekD=s0-d)
Kutukculer N et al. Front Immunol 2015 145
Kutukculer N et al. Front Immunol 2015 145
Novel primary immunodeficiency candidate genes predicted by the human gene connectome.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vtDSGMI-yEezW7P4xVGYYkjlbjLLdcDfSqDf3al8Q8qcsxBiogiQj8SslVDfzwez2cIM6UbpbkGJDzq1MNEd92BUmj0NVtjfabKOQqWNS3ENvRw7ClRekD=s0-d)
Itan Y et al. Front Immunol 2015 142
Itan Y et al. Front Immunol 2015 142
Gene therapy for primary immunodeficiencies.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vtDSGMI-yEezW7P4xVGYYkjlbjLLdcDfSqDf3al8Q8qcsxBiogiQj8SslVDfzwez2cIM6UbpbkGJDzq1MNEd92BUmj0NVtjfabKOQqWNS3ENvRw7ClRekD=s0-d)
Fischer A et al. Clin. Genet. 2015 Feb 24.
Fischer A et al. Clin. Genet. 2015 Feb 24.
Important differences in the diagnostic spectrum of primary immunodeficiency in adults versus children.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vtDSGMI-yEezW7P4xVGYYkjlbjLLdcDfSqDf3al8Q8qcsxBiogiQj8SslVDfzwez2cIM6UbpbkGJDzq1MNEd92BUmj0NVtjfabKOQqWNS3ENvRw7ClRekD=s0-d)
Abolhassani H et al. Expert Rev Clin Immunol 2015 Feb (2) 289-302
Abolhassani H et al. Expert Rev Clin Immunol 2015 Feb (2) 289-302
Wiskott-Aldrich Syndrome - April 22, 2015
What is Wiskott-Aldrich syndrome?
From the NIH Genetics Home Reference
Check out genetic conditions and tests associated with Wiskott-Aldrich syndrome,
from the NIH Genetic Testing Registry
Outcomes following gene therapy in patients with severe Wiskott-Aldrich syndrome.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vtDSGMI-yEezW7P4xVGYYkjlbjLLdcDfSqDf3al8Q8qcsxBiogiQj8SslVDfzwez2cIM6UbpbkGJDzq1MNEd92BUmj0NVtjfabKOQqWNS3ENvRw7ClRekD=s0-d)
Hacein-Bey AS et al. JAMA 2015 Apr 21. (15) 1550-1563
Hacein-Bey AS et al. JAMA 2015 Apr 21. (15) 1550-1563
New era of medicine begins as first children cured of genetic disorder,
The Telegraph, Apr 21
Clinical applications of gene therapy for primary immunodeficiencies.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vtDSGMI-yEezW7P4xVGYYkjlbjLLdcDfSqDf3al8Q8qcsxBiogiQj8SslVDfzwez2cIM6UbpbkGJDzq1MNEd92BUmj0NVtjfabKOQqWNS3ENvRw7ClRekD=s0-d)
Cicalese MP et al. Hum. Gene Ther. 2015 Apr 10.
Cicalese MP et al. Hum. Gene Ther. 2015 Apr 10.
Unraveling the repertoire in wiskott-Aldrich syndrome.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vtDSGMI-yEezW7P4xVGYYkjlbjLLdcDfSqDf3al8Q8qcsxBiogiQj8SslVDfzwez2cIM6UbpbkGJDzq1MNEd92BUmj0NVtjfabKOQqWNS3ENvRw7ClRekD=s0-d)
Petersen SH et al. Front Immunol 2014 539
Petersen SH et al. Front Immunol 2014 539
Gene therapy for Wiskott-Aldrich syndrome.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vtDSGMI-yEezW7P4xVGYYkjlbjLLdcDfSqDf3al8Q8qcsxBiogiQj8SslVDfzwez2cIM6UbpbkGJDzq1MNEd92BUmj0NVtjfabKOQqWNS3ENvRw7ClRekD=s0-d)
Bosticardo M et al. Curr Gene Ther 2014 (6) 413-21
Bosticardo M et al. Curr Gene Ther 2014 (6) 413-21
Wiskott-Aldrich syndrome: diagnosis, current management, and emerging treatments.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vtDSGMI-yEezW7P4xVGYYkjlbjLLdcDfSqDf3al8Q8qcsxBiogiQj8SslVDfzwez2cIM6UbpbkGJDzq1MNEd92BUmj0NVtjfabKOQqWNS3ENvRw7ClRekD=s0-d)
Buchbinder D et al. Appl Clin Genet 2014 55-66
Buchbinder D et al. Appl Clin Genet 2014 55-66
Severe Combined Immmuno Deficiency: Recent Insights - April 1, 2015
Hematopoietic stem cell transplantation for severe combined immunodeficiency.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vtDSGMI-yEezW7P4xVGYYkjlbjLLdcDfSqDf3al8Q8qcsxBiogiQj8SslVDfzwez2cIM6UbpbkGJDzq1MNEd92BUmj0NVtjfabKOQqWNS3ENvRw7ClRekD=s0-d)
Wahlstrom JT et al. Curr Pediatr Rep 2015 Mar 1. (1) 1-10
Wahlstrom JT et al. Curr Pediatr Rep 2015 Mar 1. (1) 1-10
Positive family history, infection, low Absolute Lymphocyte Cunt (ALC), and absent thymic shadow: diagnostic Clues for all molecular forms of Severe Combined Immunodeficiency (SCID).![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vtDSGMI-yEezW7P4xVGYYkjlbjLLdcDfSqDf3al8Q8qcsxBiogiQj8SslVDfzwez2cIM6UbpbkGJDzq1MNEd92BUmj0NVtjfabKOQqWNS3ENvRw7ClRekD=s0-d)
McWilliams L M et al. J Allergy Clin Immunol Pract 2015 Mar 27.
McWilliams L M et al. J Allergy Clin Immunol Pract 2015 Mar 27.
Successful newborn screening for SCID in the Navajo Nation.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vtDSGMI-yEezW7P4xVGYYkjlbjLLdcDfSqDf3al8Q8qcsxBiogiQj8SslVDfzwez2cIM6UbpbkGJDzq1MNEd92BUmj0NVtjfabKOQqWNS3ENvRw7ClRekD=s0-d)
Kwan A et al. Clin. Immunol. 2015 Mar 8. (1) 29-34
Kwan A et al. Clin. Immunol. 2015 Mar 8. (1) 29-34
Gene therapy for primary immunodeficiencies.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vtDSGMI-yEezW7P4xVGYYkjlbjLLdcDfSqDf3al8Q8qcsxBiogiQj8SslVDfzwez2cIM6UbpbkGJDzq1MNEd92BUmj0NVtjfabKOQqWNS3ENvRw7ClRekD=s0-d)
Fischer A et al. Clin. Genet. 2015 Feb 24.
Fischer A et al. Clin. Genet. 2015 Feb 24.
Combined immunodeficiency due to MALT1 mutations, treated by hematopoietic cell transplantation.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vtDSGMI-yEezW7P4xVGYYkjlbjLLdcDfSqDf3al8Q8qcsxBiogiQj8SslVDfzwez2cIM6UbpbkGJDzq1MNEd92BUmj0NVtjfabKOQqWNS3ENvRw7ClRekD=s0-d)
Punwani D et al. J. Clin. Immunol. 2015 Feb (2) 135-46
Punwani D et al. J. Clin. Immunol. 2015 Feb (2) 135-46
Incidence of severe combined immunodeficiency through newborn screening in a Chinese population.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vtDSGMI-yEezW7P4xVGYYkjlbjLLdcDfSqDf3al8Q8qcsxBiogiQj8SslVDfzwez2cIM6UbpbkGJDzq1MNEd92BUmj0NVtjfabKOQqWNS3ENvRw7ClRekD=s0-d)
Chien Yin-Hsiu et al. J. Formos. Med. Assoc. 2015 Jan (1) 12-6
Chien Yin-Hsiu et al. J. Formos. Med. Assoc. 2015 Jan (1) 12-6
Severe combined immunodeficiency: recent developments and guidance on clinical management.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vtDSGMI-yEezW7P4xVGYYkjlbjLLdcDfSqDf3al8Q8qcsxBiogiQj8SslVDfzwez2cIM6UbpbkGJDzq1MNEd92BUmj0NVtjfabKOQqWNS3ENvRw7ClRekD=s0-d)
Rivers L et al. Arch. Dis. Child. 2015 Jan 6.
Rivers L et al. Arch. Dis. Child. 2015 Jan 6.
Diagnosing primary immunodeficiency: a practical approach for the non-immunologist.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vtDSGMI-yEezW7P4xVGYYkjlbjLLdcDfSqDf3al8Q8qcsxBiogiQj8SslVDfzwez2cIM6UbpbkGJDzq1MNEd92BUmj0NVtjfabKOQqWNS3ENvRw7ClRekD=s0-d)
Lehman H et al. Curr Med Res Opin 2015 Apr (4) 697-706
Lehman H et al. Curr Med Res Opin 2015 Apr (4) 697-706
Newborn blood spot screening test using multiplexed real-time PCR to simultaneously screen for spinal muscular atrophy and severe combined immunodeficiency.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vtDSGMI-yEezW7P4xVGYYkjlbjLLdcDfSqDf3al8Q8qcsxBiogiQj8SslVDfzwez2cIM6UbpbkGJDzq1MNEd92BUmj0NVtjfabKOQqWNS3ENvRw7ClRekD=s0-d)
Taylor JL et al. Clin. Chem. 2015 Feb (2) 412-9
Taylor JL et al. Clin. Chem. 2015 Feb (2) 412-9
Screening for and treatments of congenital immunodeficiency diseases.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vtDSGMI-yEezW7P4xVGYYkjlbjLLdcDfSqDf3al8Q8qcsxBiogiQj8SslVDfzwez2cIM6UbpbkGJDzq1MNEd92BUmj0NVtjfabKOQqWNS3ENvRw7ClRekD=s0-d)
Verbsky J et al. Clin Perinatol 2014 Dec (4) 1001-15
Verbsky J et al. Clin Perinatol 2014 Dec (4) 1001-15
Fiscal implications of newborn screening in the diagnosis of severe combined immunodeficiency.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vtDSGMI-yEezW7P4xVGYYkjlbjLLdcDfSqDf3al8Q8qcsxBiogiQj8SslVDfzwez2cIM6UbpbkGJDzq1MNEd92BUmj0NVtjfabKOQqWNS3ENvRw7ClRekD=s0-d)
Kubiak C et al. J Allergy Clin Immunol Pract 2014 Nov-Dec (6) 697-702
Kubiak C et al. J Allergy Clin Immunol Pract 2014 Nov-Dec (6) 697-702
Higher prevalence of immune deficiency syndrome found in infants: study finds nearly twice as many newborns affected by severe combined immunodeficiency than previous research had estimated.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vtDSGMI-yEezW7P4xVGYYkjlbjLLdcDfSqDf3al8Q8qcsxBiogiQj8SslVDfzwez2cIM6UbpbkGJDzq1MNEd92BUmj0NVtjfabKOQqWNS3ENvRw7ClRekD=s0-d)
Levenson D et al. Am. J. Med. Genet. A 2014 Dec (12) vii-viii
Levenson D et al. Am. J. Med. Genet. A 2014 Dec (12) vii-viii
Newborn screening for SCID: where are we now?![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vtDSGMI-yEezW7P4xVGYYkjlbjLLdcDfSqDf3al8Q8qcsxBiogiQj8SslVDfzwez2cIM6UbpbkGJDzq1MNEd92BUmj0NVtjfabKOQqWNS3ENvRw7ClRekD=s0-d)
Buelow BJ et al. Expert Rev Clin Immunol 2014 Dec (12) 1649-57
Buelow BJ et al. Expert Rev Clin Immunol 2014 Dec (12) 1649-57
Genome editing: a tool for research and therapy: targeted genome editing hits the clinic.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vtDSGMI-yEezW7P4xVGYYkjlbjLLdcDfSqDf3al8Q8qcsxBiogiQj8SslVDfzwez2cIM6UbpbkGJDzq1MNEd92BUmj0NVtjfabKOQqWNS3ENvRw7ClRekD=s0-d)
Lombardo A et al. Nat. Med. 2014 Oct (10) 1101-3
Lombardo A et al. Nat. Med. 2014 Oct (10) 1101-3
Stem cell transplantation for primary immunodeficiency diseases: the North American experience.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vtDSGMI-yEezW7P4xVGYYkjlbjLLdcDfSqDf3al8Q8qcsxBiogiQj8SslVDfzwez2cIM6UbpbkGJDzq1MNEd92BUmj0NVtjfabKOQqWNS3ENvRw7ClRekD=s0-d)
Pai SY et al. Curr Opin Allergy Clin Immunol 2014 Dec (6) 521-6
Pai SY et al. Curr Opin Allergy Clin Immunol 2014 Dec (6) 521-6
Primary Immunodeficiency Disorders: Genetics & Public Health- October 16, 2014
CDC paper Prevalence and morbidity of primary immunodeficiency diseases, United States 2001–2007.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vtDSGMI-yEezW7P4xVGYYkjlbjLLdcDfSqDf3al8Q8qcsxBiogiQj8SslVDfzwez2cIM6UbpbkGJDzq1MNEd92BUmj0NVtjfabKOQqWNS3ENvRw7ClRekD=s0-d)
Kobrynski L, Waltenburg Powell R, Bowen S J Clin Immunol. 2014 Sep 26.
Kobrynski L, Waltenburg Powell R, Bowen S J Clin Immunol. 2014 Sep 26.
CDC information: Newborn Screening: Severe Combined Immunodeficiency (SCID)
CDC Flickr album: Newborn Screening: Family Stories includes stories from families with children affected by SCID![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vtDSGMI-yEezW7P4xVGYYkjlbjLLdcDfSqDf3al8Q8qcsxBiogiQj8SslVDfzwez2cIM6UbpbkGJDzq1MNEd92BUmj0NVtjfabKOQqWNS3ENvRw7ClRekD=s0-d)
CDC Flickr album: Newborn Screening: Public Health Stories CDC scientist Robert Vogt talks about his work on newborn screening for SCID![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vtDSGMI-yEezW7P4xVGYYkjlbjLLdcDfSqDf3al8Q8qcsxBiogiQj8SslVDfzwez2cIM6UbpbkGJDzq1MNEd92BUmj0NVtjfabKOQqWNS3ENvRw7ClRekD=s0-d)
Primary immunodeficiency disorders, mostly inherited, weaken the immune system, allowing repeated infections and other health problems to occur more easily,
from the Mayo Clinic
Global overview of primary immunodeficiencies: a report from Jeffrey Modell Centers worldwide focused on diagnosis, treatment, and discovery![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vtDSGMI-yEezW7P4xVGYYkjlbjLLdcDfSqDf3al8Q8qcsxBiogiQj8SslVDfzwez2cIM6UbpbkGJDzq1MNEd92BUmj0NVtjfabKOQqWNS3ENvRw7ClRekD=s0-d)
Vicki Modell, et al. Immunologic Research March 2014
Vicki Modell, et al. Immunologic Research March 2014
The use of databases in primary immunodeficiencies.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vtDSGMI-yEezW7P4xVGYYkjlbjLLdcDfSqDf3al8Q8qcsxBiogiQj8SslVDfzwez2cIM6UbpbkGJDzq1MNEd92BUmj0NVtjfabKOQqWNS3ENvRw7ClRekD=s0-d)
Kindle G, et al. Curr Opin Allergy Clin Immunol. 2014 Sep 15.
Kindle G, et al. Curr Opin Allergy Clin Immunol. 2014 Sep 15.
Contribution of high-throughput DNA sequencing to the study of primary immunodeficiencies.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vtDSGMI-yEezW7P4xVGYYkjlbjLLdcDfSqDf3al8Q8qcsxBiogiQj8SslVDfzwez2cIM6UbpbkGJDzq1MNEd92BUmj0NVtjfabKOQqWNS3ENvRw7ClRekD=s0-d)
Picard C, et al. Eur J Immunol. 2014 Oct;44(10):2854-61.
Picard C, et al. Eur J Immunol. 2014 Oct;44(10):2854-61.
Utility of next generation sequencing in clinical primary immunodeficiencies.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vtDSGMI-yEezW7P4xVGYYkjlbjLLdcDfSqDf3al8Q8qcsxBiogiQj8SslVDfzwez2cIM6UbpbkGJDzq1MNEd92BUmj0NVtjfabKOQqWNS3ENvRw7ClRekD=s0-d)
Raje N, et al. Curr Allergy Asthma Rep. 2014 Oct;14(10):468.
Raje N, et al. Curr Allergy Asthma Rep. 2014 Oct;14(10):468.
Newborn screening for severe combined immunodeficiency in 11 screening programs in the United States.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vtDSGMI-yEezW7P4xVGYYkjlbjLLdcDfSqDf3al8Q8qcsxBiogiQj8SslVDfzwez2cIM6UbpbkGJDzq1MNEd92BUmj0NVtjfabKOQqWNS3ENvRw7ClRekD=s0-d)
Kwan A, et al. JAMA. 2014 Aug 20;312(7):729-38.
Kwan A, et al. JAMA. 2014 Aug 20;312(7):729-38.
Guidelines for genetic studies in single patients: lessons from primary immunodeficiencies![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vtDSGMI-yEezW7P4xVGYYkjlbjLLdcDfSqDf3al8Q8qcsxBiogiQj8SslVDfzwez2cIM6UbpbkGJDzq1MNEd92BUmj0NVtjfabKOQqWNS3ENvRw7ClRekD=s0-d)
Casanova JL, et al. J Exp Med 2014 Oct
Casanova JL, et al. J Exp Med 2014 Oct
Increased safety of gene therapy for X-linked SCID,
by Rebecca Burbidge, PHG Foundation, Oct 13
Severe Combined Immunodeficiency: Newborn Screening Saves Lives - August 28, 2014
What is SCID?
Severe combined immunodeficiency is a group of genetic disorders characterized by little or no immune response. SCID is sometimes known as "bubble boy" disease. Patients are susceptible to recurrent infections. New treatments can save many SCID patients. From the National Center Biotechnology Information, NIH
Newborn screening for severe combined immunodeficiency in 11 screening programs in the United States.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vtDSGMI-yEezW7P4xVGYYkjlbjLLdcDfSqDf3al8Q8qcsxBiogiQj8SslVDfzwez2cIM6UbpbkGJDzq1MNEd92BUmj0NVtjfabKOQqWNS3ENvRw7ClRekD=s0-d)
Antonia Kwan, et al. JAMA, August 20, 2014
Antonia Kwan, et al. JAMA, August 20, 2014
Editorial: Newborn screening for severe combined immunodeficiency: Progress and challenges.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vtDSGMI-yEezW7P4xVGYYkjlbjLLdcDfSqDf3al8Q8qcsxBiogiQj8SslVDfzwez2cIM6UbpbkGJDzq1MNEd92BUmj0NVtjfabKOQqWNS3ENvRw7ClRekD=s0-d)
Neil A. Holtzman. JAMA. 2014;312(7):701-702.
Neil A. Holtzman. JAMA. 2014;312(7):701-702.
Transplantation outcomes for severe combined immunodeficiency, 2000–2009![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vtDSGMI-yEezW7P4xVGYYkjlbjLLdcDfSqDf3al8Q8qcsxBiogiQj8SslVDfzwez2cIM6UbpbkGJDzq1MNEd92BUmj0NVtjfabKOQqWNS3ENvRw7ClRekD=s0-d)
Sung-Yun Pai, et al. New England Journal Medicine, July 30, 2014
Sung-Yun Pai, et al. New England Journal Medicine, July 30, 2014
CDC information: Newborn screening: Saving Lives for 50 Years- CDC recently helped put into practice a newborn screening blood test for Severe Combined Immune Deficiency (SCID).
The long quest for neonatal screening for SCID![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vtDSGMI-yEezW7P4xVGYYkjlbjLLdcDfSqDf3al8Q8qcsxBiogiQj8SslVDfzwez2cIM6UbpbkGJDzq1MNEd92BUmj0NVtjfabKOQqWNS3ENvRw7ClRekD=s0-d)
R Buckley, J Allergy Immunology Infectious Diseases (2012)
R Buckley, J Allergy Immunology Infectious Diseases (2012)
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