Chagas Disease: Genomic Insights into a Neglected Parasitic Infection - February 20, 2015

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Chagas Disease

Chagas Disease: Genomic Insights into a Neglected Parasitic Infection - February 20, 2015

CDC information: Chagas disease is considered a neglected parasitic infection targeted for public health action

CDC paper: Genetically modifying the insect gut microbiota to control Chagas disease vectors through systemic RNAi.
Taracena Mabel L et al. PLoS Negl Trop Dis 2015 Feb (2) e0003358

Molecular genotyping of Trypanosoma cruzi for lineage assignment and population genetics.
Messenger Louisa A et al. Methods Mol. Biol. 2015 297-337

Host genetics and parasitic infections.
Mangano V D et al. Clin. Microbiol. Infect. 2014 Dec (12) 1265-75

Sequence variation in CYP51A from the Y strain of Trypanosoma cruzi alters its sensitivity to inhibition.
Cherkesova Tatiana S et al. FEBS Lett. 2014 Nov 3. (21) 3878-85

Chagas disease cardiomyopathy: immunopathology and genetics.
Cunha-Neto Edecio et al. Mediators Inflamm. 2014 683230

Genetic variability and geographical diversity of the main Chagas' disease vector Panstrongylus megistus (Hemiptera: Triatominae) in Brazil based on ribosomal DNA intergenic sequences.
Cavassin Francelisse Bridi et al. J. Med. Entomol. 2014 May (3) 616-28

Gene expression changes induced by Trypanosoma cruzi shed microvesicles in mammalian host cells: relevance of tRNA-derived halves.
Garcia-Silva Maria R et al. Biomed Res Int 2014 305239

Find out what genes have been reported in relation to Chagas disease occurrence and outcomes?Search the HuGE Navigator

Prevalence of Chagas disease in Latin-American igmrants living in Europe: A systematic review and meta-analysis.
Requena-Méndez Ana et al. PLoS Negl Trop Dis 2015 Feb (2) e0003540

Trypanosomatids topoisomerase re-visited. New structural findings and role in drug discovery.
Balaña-Fouce Rafael et al. Int J Parasitol Drugs Drug Resist 2014 Dec (3) 326-37

Trypanosoma cruzi, the causal agent of Chagas disease: Boundaries between wild and domestic cycles in Venezuela.
Herrera Leidi et al. Front Public Health 2014 259