ArrayTrack™ News

ArrayTrack™ News

SNP Library
An SNP Library has been added to the ArrayTrack™ Library collection. The SNP Library allows researchers to query SNP annotation for a list of SNPs. Furthermore, it provides SNP-related gene, protein, pathway and Gene Ontology information. (03/16/2009)

SNP Data AnalysisAn addition to the ArrayTrack™ suite that is specifically for SNP data analysis is underway. It is currently in the internal evaluation and testing phase. (03/09/09)
FDA "Commissioner’s Comments to FDA Staff" by Acting Commissioner, Frank M. Torti, MD, MPH
“NCTR has developed ArrayTrack™, a software tool that can store, analyze, and interpret DNA microarray data. Microarrays produce myriad data on gene expression that can provide added data on underlying mechanism of drug action for reviewers. To date, more than 100 FDA reviewers and scientists have been trained in the use of this software. This tool, in conjunction with the NCTR-led MicroArray Quality Control (MAQC) consortium and the Voluntary Genomics Data Submission (VGDS) process, is being used by several FDA regulatory centers to assess data voluntarily submitted by the regulated industry. This collaboration is one that identifies FDA as a catalyst in the development of new standards that will facilitate drug development.” (03/02/09)

ArrayTrack™ Successfully Implemented at Eli Lilly
On December 18, 2008, ArrayTrack™ 3.4 was set up and implemented at Eli Lilly as part of their production environment. The first trial of gene-expression data was also loaded into the stand-alone database successfully. Eli Lilly attributed the ArrayTrack™ team’s “high level of engagement, responsiveness and expertise” as the reason for “one of the best external engagements that I have experienced on an implementation project.” (02/09/09)

Eli Lilly Selects ArrayTrack™
ArrayTrack™ is a free, publicly available bioinformatics tool developed by the NCTR for FDA research and review of pharmacogenomics data submitted by the sponsors in the Voluntary Genomics Data Submission (VGDS) program. ArrayTrack™ has been expanded to other omics dataset types, and over 100 FDA scientists and reviewers have been trained to use the ArrayTrack™ tools. Recently, Eli Lilly formed an evaluation team of experts for a rigorous review of ArrayTrack's architectural structure, functional, quality, and security assessments, local installation parameters, and ability to support Eli Lilly's clinical gene-expression studies. Eli Lilly selected the ArrayTrack™ platform for their clinical gene-expression data storage and baseline analysis and further stated, “The level of commitment demonstrated by the ArrayTrack™ group strengthened our confidence in our ability to work together on some of the current gaps in making ArrayTrack™ fully functional for Lilly scientists.” (7/31/2008)

ArrayTrack™ v3.4.0 Release
Release Announcement (1/31/2008-Web version and 6/30/2008-CD version)

SimpleTox Available
SimpleTox, a batch-data uploading format, was developed based on the SEND v2.3 (Standard for Exchange of Nonclinical Data) standard and the SDTM (Study Data Tabulation Model) data model, and as such supports most nonclinical studies in conjunction with DNA microarrays. Data uploaded using SimpleTox is searchable. Learn more with the SimpleTox Tutorial. (12/31/2007)

SAM Integrated with ArrayTrack™
The R version of the very popular SAM (Significance Analysis of Microarrays, SAMR v1.25) was integrated with ArrayTrack™ allowing you to access and run SAM within ArrayTrack™ with a user-friendly interface. Enjoy! (12/31/2007)

ArrayTrack™ Supports Linux
Linux SuSE 10, Linux RedHat Enterprise 3, Linux Ubuntu 7, as well as Windows and UNIX, are supported by ArrayTrack™. (10/31/2007)

Integrating ArrayTrack™ and JANUS database
The integration of ArrayTrack™ and the JANUS database has begun. This integration will result in a complete data repository solution aggregating and integrating clinical and nonclinical study data together with DNA microarray data. (08/29/2007)


Contact Information
Collaboration information: Dr. Weida Tong (870-543-7142 or weida.tong@fda.hhs.gov)

Assistance in using ArrayTrack™: Feng Qian (870-543-7290 or feng.qian@fda.hhs.gov)
Don Ding (870-543-7685 or don.ding@fda.hhs.gov)

Submit suggestions: Dr. Hong Fang (870-543-7538 or hong.fang@fda.hhs.gov)

Report technical problems: NCTRBioinformaticsSupport@fda.hhs.gov

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ArrayTrack™ News