Cutaneous T-Cell Lymphoma: Reduced US Incidence Rates Surprise Researchers John Jesitus (++) +...

Cutaneous T-Cell Lymphoma: Reduced US Incidence Rates Surprise Researchers John Jesitus https://www.medscape.com/viewarticle/cutaneous-t-cell-lymphoma-reduced-us-incidence-rates-2026a10013fc?src= A recent analysis showed that although age-adjusted US rates of cutaneous T-cell lymphoma (CTCL) incidence rose between 2000 and 2015, the number of cases declined from 2015 to 2022 — a timeframe marked by widespread use of biologic drugs that have raised concerns about potentially inducing or exacerbating CTCL. As an epidemiologic study, the analysis did not assess causality. However, authors and a CTCL expert agreed that it is plausible that dupilumab in particular might have accounted for at least some of the downturn. Watchful Waiting Has Lasting QOL Benefit in Rectal Cancer https://www.medscape.com/viewarticle/watchful-waiting-has-lasting-qol-benefit-rectal-cancer-2026a10013eh?src= Patients who are able to undergo watchful waiting instead of immediate surgery for locally advanced rectal cancer can see lasting gains in quality of life (QOL), according to a new analysis of two clinical trials. https://www.medscape.com/index/list_13474_0