PLUTO PROJECT – Disregarded Rare Diseases IRDiRC - PLUTO PROJECT – Disregarded Rare Diseases

https://irdirc.org/pluto-project-disregarded-rare-diseases-2/ Unveiling the depth of the knowledge gap in the Universe of Rare Diseases: the PLUTO mission This article presents findings from the PLUTO mission, which explores disparities in research knowledge and drug development across rare diseases. The authors, including Virginie Hivert, our Head of Therapies and Access, collaborated within the International Rare Diseases Research Consortium (IRDiRC) to examine the underrepresentation of non-oncological rare diseases in research and development. The article also proposes a new way of visualising the ‘Rare Disease Universe’. https://link.springer.com/article/10.1186/s13023-026-04574-1