Beyond CGRP: The Search for Migraine’s Next Big Target Megan Brooks

https://www.medscape.com/viewarticle/beyond-cgrp-search-migraines-next-big-target-2026a100125z?ecd=mkm_ret_261017_mscpmrk_neuro_migraine_etid8804565&uac=148436CN&impID=8804565 For the past decade, the calcitonin gene-related peptide (CGRP) pathway has been a major focus of migraine drug development. The resulting monoclonal antibodies and gepants have transformed clinical practice, establishing CGRP as one of the most successful therapeutic targets in migraine.