Skill Checkup: A 42-Year-Old Woman With Warm, Burning Erythematous Patches on Palms That Developed into Yellow Pustules Reviewed by John S. Barbieri, MD, MBA

https://reference.medscape.com/viewarticle/warm-tender-erythematous-patches-palms-2026a1000o62?ecd=mkm_ret_260813_mscpmrk-OUS_DisReferences_etid8586285&uac=148436CN&impID=8586285 A 42-year-old White woman in the US presents to her dermatologist reporting a 4-week history of warm, tender, erythematous patches on both palms that have recently developed into 2- to 10-mm yellow pustules at varying stages of evolution, with some of the lesions having transformed into brown macules. The patient reports that the lesions are accompanied by a burning sensation and pruritus. The patches are symmetric and involve the thenar and hypothenar eminences and central palms. There is overlying desquamation in areas of partially resolved pustules.