Bartter Syndrome Updated: Jul 02, 2026 Author: Lynda A Frassetto, MD; Chief Editor: Vecihi Batuman, MD, FASN

https://emedicine.medscape.com/article/238670-overview?ecd=mkm_ret_260813_mscpmrk-OUS_DisReferences_etid8586285&uac=148436CN&impID=8586285 Bartter syndrome, originally described by Bartter and colleagues in 1962, [1] represents a set of closely related, autosomal recessive renal tubular disorders characterized by hypokalemia, hypochloremia, metabolic alkalosis, and hyperreninemia with normal blood pressure. [2] (One form of Bartter syndrome, type V, discussed below, is autosomal dominant.) The underlying kidney abnormality results in excessive urinary losses of sodium, chloride, and potassium.