Does High-Dose Vitamin D3 Supplementation Improve CRC Survival? Edited by Katie Lennon +++ +++

Does High-Dose Vitamin D3 Supplementation Improve CRC Survival? Edited by Katie Lennon https://www.medscape.com/viewarticle/does-high-dose-vitamin-d3-supplementation-improve-crc-2026a1000qib?ecd=mkm_ret_260814_mscpmrk-OUS_ICYMI_etid8586335&uac=148436CN&impID=8586335 High-dose vitamin D3 supplementation added to standard chemotherapy plus bevacizumab does not improve progression-free survival (PFS) compared with standard-dose vitamin D3 in patients with previously untreated metastatic colorectal cancer (mCRC). Among 455 randomized patients, median PFS was 11.8 months in the high-dose group vs 10.3 months in the standard-dose group, with no significant differences in objective response rates or overall survival. Coronary Artery Calcium Scoring May Refine Heart Risk Estimate and Statin Decisions Edited by Archita Rai https://www.medscape.com/viewarticle/coronary-artery-calcium-scoring-may-refine-heart-risk-2026a1000qhq?ecd=mkm_ret_260814_mscpmrk-OUS_ICYMI_etid8586335&uac=148436CN&impID=8586335 Adding coronary artery calcium (CAC) scoring to risk estimates helped better identify adults at lower and higher risk for atherosclerotic cardiovascular disease (ASCVD) events. People with no detectable CAC had lower observed risk, while those with CAC had higher observed risk, especially when the decision about starting a statin was uncertain. The Coming ‘Tsunami’: Cardiac Effects of Cancer Therapy Carolyn Brown https://www.medscape.com/viewarticle/coming-tsunami-cardiac-effects-cancer-therapy-2026a1000qbr?ecd=mkm_ret_260814_mscpmrk-OUS_ICYMI_etid8586335&uac=148436CN&impID=8586335 Higher Protein Intake Not Linked to Kidney Function Decline in Middle-Aged and Older Adults https://www.medscape.com/viewarticle/higher-protein-intake-not-linked-kidney-function-decline-2026a1000qt2?ecd=mkm_ret_260814_mscpmrk-OUS_ICYMI_etid8586335&uac=148436CN&impID=8586335 Opinions Shifting on Coupling Metformin and Exercise https://www.medscape.com/viewarticle/opinions-shifting-coupling-metformin-and-exercise-2026a1000qg7?ecd=mkm_ret_260814_mscpmrk-OUS_ICYMI_etid8586335&uac=148436CN&impID=8586335 Scientists May Have a New Explanation for Excessive Sweating https://www.medscape.com/viewarticle/scientists-may-have-new-explanation-excessive-sweating-2026a1000qr1?ecd=mkm_ret_260814_mscpmrk-OUS_ICYMI_etid8586335&uac=148436CN&impID=8586335