Modeling infectious disease dynamics S Cobey, Science, May 15, 2020

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 Coronavirus

Modeling infectious disease dynamics
S Cobey, Science, May 15, 2020

The early spread of SARS-CoV-2 has revealed critical information about the potential size of the pandemic, if it were allowed to grow unchecked. This information has mathematical foundations developed from modeling other infectious diseases.

Wrong but Useful — What Covid-19 Epidemiologic Models Can and Cannot Tell Us
I Holmdahl et al, NEJM, May 15, 2020

Infectious disease modeling is an expansive field with a long history, encompassing a range of methods and assumptions that are not necessarily directly comparable, or even designed for the same purpose. There are five questions to ask about epidemiologic models.

Proteomics of SARS-CoV-2-infected host cells reveals therapy targets
D Bojkova et al, Nature, May 14, 2020

Analysis of SARS-CoV-2 RNA-Sequences by Interpretable Machine Learning Models
T Villman et al, BIORXIV, May 15, 2020

Evolution and molecular characteristics of SARS-CoV-2 genome
Y Bai et al, BIORXIV, May 15, 2020