Clinical Trials Update from NCI, May 2020

Clinical Trials Update from NCI, May 2020

Clinical Trials
Updates from the National Cancer Institute
Clinical Trials News
		NCI COVID-19 in Cancer Patients Study (NCCAPS) The NCI COVID-19 in Cancer Patients Study, or NCCAPS, is a natural history study of COVID-19 in people with cancer. As part of the NCCAPS study, researchers will collect blood samples, medical information, and medical images from 2,000 people with cancer who also have COVID-19. Each person will be followed for up to 2 years to help doctors understand how cancer affects COVID-19 and COVID-19 affects cancer.
		Effective, Less Toxic Treatment for Adults with Burkitt Lymphoma In a new study, a treatment regimen that is less toxic than standard dose-intensive chemotherapy was found to be highly effective for adults with Burkitt lymphoma across all age groups, regardless of HIV status. Besides being better tolerated, the regimen, called dose-adjusted (DA) EPOCH-R, is already an option for diffuse large B-cell lymphomas and can be given in an outpatient setting.
		PSMA PET-CT Detects Prostate Cancer Spread, Trial Shows For some men with prostate cancer at high risk of spreading, a large clinical trial shows an imaging procedure called PSMA PET-CT is more likely to detect tumors that have spread than the standard imaging approaches used in many countries.
		Encorafenib, Cetuximab Combination Approved for Colorectal Cancer That Has Spread The Food and Drug Administration (FDA) has approved encorafenib (Braftovi) with cetuximab (Erbitux) to treat adults with colorectal cancer that has spread and whose tumors have a change in the BRAF gene, called V600E.
		For Women with Breast Cancer, Regular Exercise May Improve Survival Women with high-risk breast cancer who engaged in regular exercise before their cancer diagnosis and after treatment were less likely to have their cancer return or to die compared with women who were not active, a recent study found. The study was embedded in a large NCI-funded clinical trial.
Clinical Trials Information for Patients and Caregivers
Types of Clinical Trials There are many types of clinical trials. Each type is designed to answer different research questions and will help researchers learn things that will help people in the future. Learn more about natural history studies and other types of trials.
Help Finding NCI-Supported Clinical Trials This page explains how to use the clinical trials search form on NCI’s website to find NCI-supported clinical trials and review the results of your searches.
		Search for NCI-Supported Clinical Trials Use our search form to find a clinical trial or other research study that may be right for you or a loved one.
NCI-Supported Clinical Trials That Are Recruiting Patients
Mapping Lymph Nodes to Prevent Lymphedema This phase 3 trial studies how well axillary reverse mapping works in preventing the swelling of lymph nodes (lymphedema) in patients with breast cancer undergoing axillary lymph node dissection. Axillary reverse mapping may help to preserve the lymph node drainage system around the breast to prevent lymphedema after surgery.
Preventing Second Cancers in Colon Cancer Survivors In this phase 3 trial, people who have had curative surgery for colon cancer will be randomly assigned to take sulindac and a placebo, eflornithine and a placebo, both sulindac and eflornithine, or two placebo pills for 36 months. Doctors want to see if sulindac, eflornithine, or the combination of both drugs decreases the recurrence of high-risk adenomas or the development of new colon or rectal cancers.