Methylene blue inhibits Caspase-6 activity, and reverses Caspase-6-induced cognitive impairment and neuroinflammation in aged mice | Acta Neuropathologica Communications | Full Text

Methylene blue inhibits Caspase-6 activity, and reverses Caspase-6-induced cognitive impairment and neuroinflammation in aged mice | Acta Neuropathologica Communications | Full Text

Acta Neuropathologica Communications

Methylene blue inhibits Caspase-6 activity, and reverses Caspase-6-induced cognitive impairment and neuroinflammation in aged mice

Activated Caspase-6 (Casp6) is associated with age-dependent cognitive impairment and Alzheimer disease (AD). Mice expressing human Caspase-6 in hippocampal CA1 neurons develop age-dependent cognitive deficits...

Authors:Libin Zhou, Joseph Flores, Anastasia Noël, Olivier Beauchet, P. Jesper Sjöström and Andrea C. LeBlanc

Citation:Acta Neuropathologica Communications 2019 7:210

Content type:Research

Published on: 16 December 2019

• ViewFull Text
 
• ViewPDF