Tools for immune-oncology research

February 8, 2018     Microbiology     The latest microbiology news from the AZoNetwork

Tools for immune-oncology research Cancer immunotherapies are efficient and have durable effects, but to fully unleash the power of immunotherapy against cancer requires identification of biomarkers to predict patient response. Read Full Article Here

Deciphering Antibodies with Next-Generation Protein Sequencing Technology   Randomness in the generation of antibodies makes each antibody unique and effectively makes any sequences in any databases untrustworthy. NGPS can be used to determine the heavy and light chain sequences and determine full protein sequences from protein samples using mass spectrometry.    Learn More           Researchers show association between microbiome and cancer-related blood infections   Cancer patients receive essential medicines, fluids, blood and nutrients through long, flexible tubes called central venous catheters, or central lines.

Study adds more evidence that intestinal microbiome plays substantial role in obesity   A new Johns Hopkins study of mice with the rodent equivalent of metabolic syndrome has added to evidence that the intestinal microbiome -; a "garden" of bacterial, viral and fungal genes -; plays a substantial role in the development of obesity and insulin resistance in mammals, including humans.       Microbiome research offers new clues to increased HIV risk in women   Drawing from data collected for years by AIDS researchers in six African nations, scientists have pinpointed seven bacterial species whose presence in high concentrations may significantly increase the risk of HIV infection in women.       Researchers find transient effects of food preservative on gut microbiome   Antimicrobial compounds added to preserve food during storage are believed to be benign and non-toxic to the consumer, but there is "a critical scientific gap in understanding the potential interactions" they may have with the hundreds of species of microbes in our intestines, say David Sela, a nutritional microbiologist at the University of Massachusetts Amherst, and colleagues.       Soil-dwelling bacterium produces potential weapon against melanoma   A type of soil-dwelling bacterium produces molecules that induce death in melanoma cells, research at Oregon State University shows.

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