Breast Cancer Res Treat. 2017 Nov 21. doi: 10.1007/s10549-017-4584-y. [Epub ahead of print]
BRCAsearch: written pre-test information and BRCA1/2 germline mutation testing in unselected patients with newly diagnosed breast cancer.
Nilsson MP1,2, Törngren T3, Henriksson K4, Kristoffersson U4,5, Kvist A3, Silfverberg B4, Borg Å3, Loman N3,6.
In a prospective, single-arm study, comprehensive BRCA1/2 testing was offered to unselected patients with newly diagnosed breast cancer at three hospitals in south Sweden (BRCAsearch, ClinicalTrials.gov Identifier: NCT02557776). Pre-test information was provided by a standardized invitation letter, but the patients could contact a genetic counselor for telephone genetic counseling if they felt a need for that. Noncarriers were informed about the test result through a letter. Mutation carriers were contacted and offered an appointment for in-person post-test genetic counseling.
Breast cancer; Counseling; Genetic testing; Unselected