domingo, 23 de abril de 2017

Analysis Suggests Wider Use for PARP Inhibitors. - PubMed - NCBI

Analysis Suggests Wider Use for PARP Inhibitors. - PubMed - NCBI



 2017 Apr 12. doi: 10.1158/2159-8290.CD-NB2017-049. [Epub ahead of print]

Analysis Suggests Wider Use for PARP Inhibitors.

[No authors listed]

Abstract

Researchers have developed a new tool, HRDetect, to pinpoint tumors that display BRCA deficiency but don't harbor BRCA1/2 mutations. Evaluating their method in breast, ovarian, and pancreatic cancers, they identified patients whose tumors were potentially vulnerable to PARP inhibition but who didn't carry these mutations.

PMID:
 
28404569
 
DOI:
 
10.1158/2159-8290.CD-NB2017-049




From HuGE Literature Finder Database
This database contains published literature on genetic associations and other human genome epidemiology

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