Prostate Cancer, Nutrition, and Dietary Supplements (PDQ®)–Health Professional Version

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Changes to This Summary (04/19/2016)

The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.

Green Tea

This section was comprehensively reviewed.

Pomegranate

Added text to state that a phase III placebo-controlled trial of pomegranate juice and extract did not show a significant increase in prostate-specific antigen (PSA) doubling time (PSADT).

Added text to state that a phase III placebo-controlled trial of 183 patients who were randomly assigned to the pomegranate juice, pomegranate extract, or placebo did not significantly prolong PSADT in prostate cancer patients with rising PSA after primary therapy; some data from this study suggested that a subgroup analysis should be done to further investigate a potential unique sensitivity (cited Pantuck et al. as reference 20).

Vitamin D

Revised text to state that administration of calcitriol was discontinued until hypercalcemia resolved; supplementation was restarted after two weeks.

This summary is written and maintained by the PDQ Integrative, Alternative, and Complementary Therapies Editorial Board, which is editorially independent of NCI. The summary reflects an independent review of the literature and does not represent a policy statement of NCI or NIH. More information about summary policies and the role of the PDQ Editorial Boards in maintaining the PDQ summaries can be found on the About This PDQ Summary and PDQ® - NCI's Comprehensive Cancer Database pages.

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