Added text to state that an unselected cohort of 810 women of Mexican ancestry with breast cancer were tested; 4.3% had a BRCA mutation. Eight of the 35 mutations identified were the BRCA1 exon 9–12 deletion (cited Torres-Mejía as reference 72).
Updated National Comprehensive Cancer Network as reference 89.
Revised text to state that the risk of contralateral breast cancer (CBC) was 1.8-fold higher in those with a first-degree relative with breast cancer in the Women's Environmental Cancer and Radiation Epidemiology Study (WECARE) study. Also added text about a study of 810 women with stage I or stage II breast cancer who had a BRCA1 orBRCA2 mutation identified in the family; in this cohort, 149 developed CBC; the 15-year actuarial risk was 36.1% among BRCA1 mutation carriers and 28.5% among BRCA2 mutation carriers. Risks were higher among those diagnosed before age 50 years, and the risk of CBC varied by family history among women whose initial breast cancer was diagnosed before age 50 years (cited Metcalfe et al. as reference 305).
ver historia personal en: www.cerasale.com.ar [dado de baja por la Cancillería Argentina por temas políticos, propio de la censura que rige en nuestro medio]//
weblog.maimonides.edu/farmacia/archives/UM_Informe_Autoevaluacion_FyB.pdf - //
weblog.maimonides.edu/farmacia/archives/0216_Admin_FarmEcon.pdf - //
www.proz.com/kudoz/english_to_spanish/art_literary/523942-key_factors.html - 65k - // www.llave.connmed.com.ar/portalnoticias_vernoticia.php?codigonoticia=17715 // www.frusculleda.com.ar/homepage/espanol/activities_teaching.htm // http://www.on24.com.ar/nota.aspx?idNot=36331 ||